Are you interested in DNA replication, genome stability and cancer development? A PhD position is available in our group 🧬🔬 Come and join us Institute of Biophysics of the Czech Acad. Sci. Akademie věd ČR Brno ibp.cz/en/offers/job-…

A female biologist with 4 kids has fled Ukraine 🇺🇦 and now is looking for a research position in the Netherlands 🇳🇱. She is experienced with molbio and is getting her second degree in Bioinformatics. Please RT and contact me or @MrsElenaMelnik directly, if you can help

My mother left Ukraine 🇺🇦 and is now in the Czech Republic 🇨🇿 looking for a job. She is a chemical engineer/chemist specialising in polymers and has extensive experience as a sales manager. Speaks Eng/Ru/Ukr. Please DM me if you have offers/know someone in 🇨🇿/EU/UK and retweet!

When the war is over, I'm prepared to go to Ukraine and teach molecular biology/epigenetics in Master/PhD programs on site and help to prepare Ukrainian students for career in science. Two weeks a year I can commit for a few years in a row. And I think I won't be alone, oder?

I’m a bit slow today it seems! New work from the lab by Alina and Kamila and colleagues, on the impact of PARP inhibitors on Okazaki fragments (well done guys!)! nature.com/articles/s4159…

To join the seminar of Petr Cejka, please register at: us06web.zoom.us/webinar/regist…

Are you looking for a postdoc position to study 3D chromatin structure and transcription? We have three posts open for molecular biologists, imaging experts and cell biology. Please get in touch if you would like to chat!

Happy to share our manuscript about how “Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations” which is now online in Mol Cell cell.com/molecular-cell…

Congratulations to members of the Doherty laboratory @GDSC_Sussex on the publication of their latest study describing the molecular basis for the initiation of #DNA primer synthesis. Read more⬇️ nature.com/articles/s4158…

Primers are essential to #DNA replication, but how are they made? New work reveals the crystal structure of a primer initiation complex and shows that the catalytic domain of Prim-Pol enzymes is sufficient to start primer formation. Katerina Zabrady @CisnerosRes ow.ly/Phqy50J1J1G

Ok, in 24 hours, more than 40 défense systems were revealed 🤩🤯🥳. Two different approaches, congratulations to all the authors! Amazing to see the role of mobile elements in these. Maybe as @epcrocha says, cells are just battlefields for MGE! So much cool biology to understand

Happy to share our work reconstituting DNA replication with purified human proteins in nature. I worked on this in the last year of my postdoc @MRC_LMB - fantastic to see the great work the team has done since then and the finished product! Congrats all! nature.com/articles/s4158…

Happy to report that this study is now published #openaccess nature.com/articles/s4159…

Smc5/6 aids chromosome replication & repair while restraining viral DNA species. Our new work reports the first DNA-bound structure of Smc5/6. Congrats to all authors, particularly Shibai from Xiaolan Zhao Lab & You Yu from Patel Lab at @MSKCANCERCENTER 1/5 pnas.org/doi/10.1073/pn…

First C.elegans paper from the lab! Find out why C.elegans needs two proteins to bind the telomeric G-overhang. School of Biology BSRC St Andrews biorxiv.org/content/10.110…

Today in partnership with EMBL-EBI, we’re releasing predicted structures for nearly all catalogued proteins known to science, which will expand the #AlphaFold database by over 200x - from nearly 1 million to 200+ million structures: dpmd.ai/AF-22-TW 1/

New DNA replication research from @GDSC_Sussex Katerina Zabrady et al!: Reverse transcriptases prime DNA synthesis academic.oup.com/nar/article/do…

Did you know that reverse transcriptases are capable of de novo DNA primer synthesis? It has been an surprising and incredibly exciting journey. Many thanks to all members of the Doherty lab for their fantastic work. academic.oup.com/nar/advance-ar…