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Delighted to say our latest paper has just come out Huge thanks to all those involved eur03.safelinks.protection.outlook.com/?url=https%3A%…

Thank you so much Prof Jo Spencer Jo Spencer Lab for a fascinating exploration of how #imc #imaging #masscytometry in tissue-based research can reveal surprising scientific findings...🔬🦠🧬🎆🫢 #tcell #GALT #autoimmunediseases #Lupus School of Immunology & Microbial Sciences Chokshi Lab London Dr Antonio Riva

Gut-associated lymphoid tissue: a microbiota-driven hub of B cell immunity dlvr.it/T39fjH #immunology

Our review for Trends on the current knowledge of GALT is now out. We discuss its organisation, the role of GALT in B cell development, its role in autoimmunity and T cell help to B cells. Thanks to Jo Spencer Lab and Mike Pitcher for the collaboration. doi.org/10.1016/j.it.2…

Our review of the current knowledge of GALT is out now in Trends in Immunology ! In collab with Mats Bemark, we discuss GALT organisation, B/T cell interactions, responses to microbiota, and links between GALT and autoimmunity doi.org/10.1016/j.it.2…

Our latest paper is out now in Nature Communications!  Lucia Montorsi and Mike Pitcher from our lab and collaborators identified characteristics of autoimmune diseases as normal components of the immune system in human gut: nature.com/articles/s4146…

Gut-associated lymphoid tissue: a microbiota-driven hub of B cell immunity. Check out this review by Mats Bemark & @jospencerlab in Trends in Immunology #ASMicrobe hubs.li/Q02BRYMH0

Lots of amazing work on display at Spatial Biology Research @ King’s symposium, a pleasure for our postdoc Mike Pitcher to showcase our work with the Spatial Biology Facility, using @nanostringtech CosMX to study B cells in gut lymphoid tissue School of Cancer & Pharmaceutical Sciences Jelmar

After leaving the bone marrow, transitional B cells split into subsets w/ biased expression of homing receptors and different surface IgM levels. Spencer & Dionisi Jo Spencer Lab discuss how this could contribute to human lymphoid tissue content & function hubs.la/Q02JSNWX0

Our latest perspective piece is out now in Journal of Experimental Medicine! Here we propose that recruitment of immature B cells could contribute to human lymphoid tissue structure and function. rupress.org/jem/article/22…

Immature B cell homing shapes human lymphoid tissue structure and function. A new Perspective by Jo Spencer & Chiara Dionisi Jo Spencer Lab School of Immunology & Microbial Sciences hubs.la/Q02JSMGr0

Could tolerance to DNA be broken in the gut in systemic lupus erythematosus? In our latest review we explore whether tolerance to DNA can be broken when undigested DNA from microbiota in GALT directly encounters B cells unrestricted by T cell dependence doi.org/10.1016/j.imle…