🏃Dapagliflozin and Physical and Social Activity in #HFrEF #DAPA -HF

💊DAPA vs placebo

📌↗️mean KCCQ physical and social activity limitation scores at 8 months

📌↗️each of the individual components that comprise the physical and social activity limitations

📌largest…

Prof. Køber & Dr. Jawad Haider Butt MD at #ESCCongress in a joint session on treatment of #HF w/ mid-range and preserved #EF

Prof. Køber guided us nicely through RCTs in the area & Dr Jawad Haider Butt MD revealed new results from the #DELIVER trial – adding to the list of #dapa benefits!

⚠️ #HF , #COPD and efficacy of dapagliflozin in HFmrEF/HFpEF: Insights from DELIVER⚠️
Just presented at the #ESCCongress and simultaneous publication on #EJHF

HFAPresident Antonio Cannata' European Society of Cardiology European Society of Cardiology Journals Henry Han Djawid Hashemi Marco Metra Gianluigi Savarese

Geographic differences in patients with acute myocardial infarction: insights from the #PARADISE -MI.

doi.org/10.1002/ejhf.2…

HFAPresident #EJHF EJHF Editor-in-Chief Antonio Cannata' European Society of Cardiology European Society of Cardiology Journals Henry Han 
Marco Metra Gianluigi Savarese Daniela Tomasoni Djawid Hashemi @JavadHButt

BE READY!
Simultaneous publications at EJHF and presentations at ESC Congress!
Attend ESC Congress and read online at EJHF

Post hoc analysis found gout common in HF and associated w/ worse outcomes. Benefit of dapagliflozin consistent in patients with & without gout. Dapagliflozin reduced initiation of new treatments for hyperuricemia and gout. ja.ma/3Us3hZX University of Glasgow Heart Failure Research Group Jawad Haider Butt MD

Forhold mellem talje og højde er bedre indikator end BMI til at vurdere prognosen for hjertesvigtpatienter, viser ny undersøgelse, som læge og ph.d.-studerende Jawad Butt står bag #sundpol
buff.ly/3V8Gtyv

Very proud to share this analysis of #PARADIGMHF on anthropometric measures and adverse outcomes in 👥with #HF rEF published in Eur Heart J European Society of Cardiology Journals
🔥No evidence for an #obesity -survival paradox in #HF rEF
🔥📈adiposity defined by newer indices clearly associated with ⬆️ #HF 🏥

🌏Geographic Differences in Patients With Acute Myocardial Infarction in The #PARADISE -MI Trial

👉Rates of incident HF varied almost 6️⃣-fold among regions
👉effect of sacubitril/valsartan was not modified by region.

📥 onlinelibrary.wiley.com/doi/epdf/10.10…

Will definitely be THE meeting for the latest in HF!
Looking forward to presenting data on the efficacy & safety of #dapa according to #PAD status in pts with HF across the spectrum of LVEF in a pooled analysis of #DAPA -HF & #DELIVER !

🆕 study in #JACCHF found the absolute benefits of the SGLT2 inhibitor dapagliflozin is > in Black patients in part due to having a higher incidence & prevalence of #heartfailure , but the relative benefits are consistent in both Black & White patients. bit.ly/3UeMAks

New in #JACCHF :
Dapagliflozin confers similar relative risk reduction of clin outcomes in Black and White patients with Heart Failure, but Black patients benefit more due to higher absolute risk.
shorturl.at/deEJZ JACC Journals Jawad Haider Butt MD Rudolf de Boer University of Glasgow Heart Failure Research Group

Dapagliflozin in Black and White Patients With #HF Across the #EF Spectrum

DAPA-HF ➕DELIVER
🎯composite of worsening HF or CV☠️.

👥74.5% White and 10.8% Black
🎯1️⃣16.8 in Black vs 11.6 per 100 person-years in White

👉dapagliflozin ⤵️ the risk of the primary endpoint to the…

Fantastic paper now online in #EurHeartJournal led by Jawad Haider Butt MD

Important paper from the #EHJ that hopefully close the discussion on the #obesityparadox in #patients with #HF . Congratulations to Jawad Haider Butt MD & Prof. John McMurray 👏👏 EHJ Editor-in-Chief

👉 Newer indices that do not incorporate #weight showed that greater academic.oup.com/eurheartj/adva……

Anthropometric measures and adverse outcomes in heart failure with reduced ejection fraction: no evidence for an ‘obesity-survival paradox’ according to new data.
ow.ly/pkTE50Nq0z2
#HF #Heartfailure #Obesity #BMI #cardiotwitter European Society of Cardiology Journals European Society of Cardiology

Obesity paradox in heart failure: recent data discussed in a new editorial paper.
#obesity #BMI #heartfailure #HF #cardiotwitter European Society of Cardiology Journals European Society of Cardiology
ow.ly/IzNf50NpZK3

Muthu Vaduganathan Henry Woodford Dr.Rajiv Sankaranarayanan Asan Akpan Mikhail Kosiborod Ankeet S. Bhatt, MD, MBA Alfonso Valle Diego Segura-Rodríguez Shelley Zieroth Pardeep S Jhund Prabhakar Dorairaj Peder L. Myhre 🫀 Brendon Neuen British Geriatrics Society EuGMS - European Geriatric Medicine Society Jawad Haider Butt MD Among the n=1487 most frail, numerically more discontinuation rates of study drug due to AE with placebo

Improvement in health related quality of life occurred early and was greater in patients with a higher level of frailty