Desvendado mecanismo de envelhecimento que contribui para o aparecimento de linfomas publico.pt/2024/08/10/cie…

Before joining #i3S, researcher José Pedro Castro was at #Harvard Medical School working on #aging mechanisms leading to B cell lymphomas. A paper on the results, whose 1st author is José Pedro, has just been published in the journal @Natureaging. #i3Snews #cancer #cancerresearch

🧵1/5: Thrilled to share our latest paper in Nature Aging ! nature.com/articles/s4358…

Season 2, Episode 7 - The Power of Single-Cell Epigenetic Profiling with Alex Trapp We explore the cutting-edge development of single-cell epigenetic clocks and their potential applications in the field of longevity science. Episode here - open.spotify.com/episode/24Oy7Q…

📎Now with a News & Views from Pérez et al nature.com/articles/s4358… rdcu.be/dVG6I

Thanks for highlighting our work! nature.com/articles/s4358… with this spot on piece of #News&Views Nature Aging

Thanks Elsa Logarinho ! ❤️🙏🏻

🎉 Thrilled to share our work in Nature Communications! We found centenarians have (slightly) fewer harmful genetic variants - suggesting depletion of damaging mutations contributes to exceptional longevity. Incredible collaboration with Nir Barzilai, Zhengdong Zhang Sofiya Milman

glad to be a co-author of this paper profiling the transcriptomic age of single PBMC cells in humans published in Communications Biology the hard work of talented graduate student Enikő Zakar-Polyák and epigenetics aging clock expert Csaba Kerepesi (formerly of Gladyshev Lab) now of

Depletion of loss-of-function germline mutations in centenarians reveals longevity genes nature.com/articles/s4146…

Causal inference for epigenetic ageing go.nature.com/40uGAJk #ToolsoftheTrade by @kejunying

🥳Glad to see my short perspective Nature Reviews Genetics is out today! In this piece, I discussed the application of genetic-based causal inference to identify true causal factors in aging, which may help develop more reliable biomarkers or interventions.

Depletion of loss-of-function germline mutations in centenarians reveals longevity genes Kejun (Albert) Ying Zhengdong Zhang Sofiya Milman 🎗️ José Pedro Castro, PhD @AnastasiaShind Ludger Mahdi Moqri, PhD Nir Barzilai Gladyshev Lab and coauthors. 🔗nature.com/articles/s4146… Nature Communications

New online│ News and Views by José Pedro Castro, PhD on a study showing that metformin improves health markers in aged monkeys, hinting at its potential to slow aging and extend health span! #Aging 🕰️🐒 Link: 👇 nature.com/articles/s4168…

Thank you for sharing my News&Views on Metformin, Monkeys and Aging David Sinclair 😎

Some exciting news to share! Our lab is relocating to the Department of Biochemistry and Molecular Genetics (med.virginia.edu/bmg/) UVA School of Medicine in January 2025! We're actively recruiting talented postdocs to join our team. Please RT to spread the word.

Os maravilhosos genes das pessoas centenárias. Uma conversa que nos leva até ao início de tudo, ao embrião. publico.pt/2024/12/19/cie… i3S-Instituto de Investigação e Inovação em Saúde; José Pedro Castro, PhD; Vadim Gladyshev

Super excited to share our new study from the Jason Buenrostro Lab in nature! We developed a computational method for tracking transcription factor and nucleosome binding using single-cell ATAC-seq and deep learning. Paper: nature.com/articles/s4158…

O ch€ga não quer Miguel Arruda sentado ao lado da sua bancada. Disse que não se responsabiliza pelo que possa acontecer. O ch€ga não é capaz de pôr ordem na sua bancada, mas acha que o pode fazer na sociedade. 😩

José Pedro Castro do @I3S_UPorto estuda os mecanismos celulares e moleculares que governam o processo de envelhecimento. buff.ly/7Jru3aw #90SegundosCiência