(PMID: 35801078) This review from Dr. Jun-Ichi Abe et al. discussed the role of #NAD+ depletion in instigating #SASP and its downstream signaling and regulatory mechanisms that lead to the premature onset of atherosclerotic CVD in #cancer survivors. oaepublish.com/articles/jca.2…

This New Original Research Article from Dr. Dr. Jennifer DuPont, PhD et al. finds #AT2R as a #sex-specific target for #microvascular dysfunction and #aging-associated #cardiovascular disease. oaepublish.com/articles/jca.2…

(PMID: 35531366) This review from Dr. Ali J. Marian discussed the #genetic basis of human aging by focusing on two ends of the spectrum of #aging, namely rare progeria and progeroid syndromes on one end and #longevity on the other. oaepublish.com/articles/jca.2…

(PMID: 38235057) Dr Emma L. Robinson et al. commented on an article thought that the intersection of factors that modify epigenetic clocks and how that impacts organ function will expand our understanding of contributors that change the trajectory of aging oaepublish.com/articles/jca.2…

(PMID: 35891702) This review from Dr. W. H. Wilson Tang et al. focused on recent advances in their understanding of the interplay between the gut #microbiota and CVD, emphasizing the role of #cardiovascular #aging and sarcopenia in #HF. oaepublish.com/articles/jca.2…

The Original Research Article from Dr. Dao Wen Wang et al. provided fresh insights into the potential role of #FBN1 rare variants in #DCM, pointing to new directions for future genetic studies and potential therapeutic strategies in DCM management. oaepublish.com/articles/jca.2…

(PMID: 36337728) This review from Dr. Matthew J. Rossman et al. highlighted emerging topics for the promotion of healthy #CV #aging, with a particular focused on vascular function, and select discussions on blood pressure (BP). oaepublish.com/articles/jca.2…

(PMID: 38455511) Dr. Priyatansh Gurha et al. commented on an article by Li et al., which the study highlighted the importance of metabolism in regulating cardiac gene expression and underscores its significant role in cardiac myocyte proliferation. oaepublish.com/articles/jca.2…

(PMID: 37362388) This review from Dr. Massoud A. Leesar et al. summarized underlying mechanisms leading to #BRS failure and provided insights into optimizing BRS deployment by intravascular imaging. oaepublish.com/articles/jca.2…

(PMID: 37538440) Original Article from Dr Xander H. T. Wehrens et al. showed the mTAC procedure yields a highly reproducible phenotype consisting of LV contractile dysfunction and enlargement, combined with left atrial enlargement and diastolic dysfunction oaepublish.com/articles/jca.2…

(PMID: 36819765) Dr. Toren Finkel et al. commented on an article by Suda et al. thought that harnessing the #immune system represents a new and potentially powerful strategy to clear #senescent cells and potentially treat a host of #age-related #CVD. oaepublish.com/articles/jca.2…

(PMID: 37274126) This review from Dr. Konstantinos Drosatos et al. reviewed the structural and functional changes in the aged cardiovascular system and the underlying signaling pathways that are involved in #cardiovascular #aging. oaepublish.com/articles/jca.2…

(PMID: 35497092) Dr. Richard T. Lee et al. commented on an article thought that the strong human and mouse data from this report, in combination with other recent students, will likely generate excitement about the potential role of #PLA2G7 in #CV #aging. oaepublish.com/articles/jca.2…

(PMID: 37274127) This review from Dr. Dao-Fu Dai et al. focused on downstream pathways regulated by mTOR and will briefly discuss the upstream regulators of #mTOR. oaepublish.com/articles/jca.2…

Dr. Enzo R. Porrello et al. commented on an article by Alexanian et al., which the study provided novel insight into the transcriptional landscape of cardiac #fibrosis and #heart #failure. oaepublish.com/articles/jca.2…

The Original Research Article from Dr. Inna Rabinovich-Nikitin et al. demonstrated that #RORα regulates autophagic processes linked to #aging upon activation with #Nobiletin. oaepublish.com/articles/jca.2…

Dr. Georgina M. Ellison-Hughes commented on an article thought that the impact of targeted #LNP/mRNA therapeutic approaches is likely to generate ‘off-the-shelf’ products which are scalable, easy to apply, and cost-effective to prevent and treat diseases. oaepublish.com/articles/jca.2…

(PMID: 37484982) This review from Dr. Carmen C. Sucharov et al. emphasized the potential of the secretome for biomarker discovery, and discussed the difficulties on investigating the role of secreted factors and novel directions on secretome research. oaepublish.com/articles/jca.2…

(PMID: 36776272) Dr. Christopher C .Glembotski et al. commented on an article by Statzer et al. thought that ATF4 and H2S's future utility in the aging human population will require extensive studies to determine whether there are optimal levels of each. oaepublish.com/articles/jca.2…

(PMID: 38235056) The Original Research Article from Dr. Feng Cheng et al. determined the association between increased INR and the usage of warfarin by using the pharmacovigilance data from the #FDA Adverse Event Reporting System (FAERS). oaepublish.com/articles/jca.2…