ICMUB
@icmub
Institute of Molecular Chemistry @CNRS UMR6302 @dijon @univbourgogne @Univ_BFC
ID: 247280750
http://www.icmub.com 04-02-2011 13:36:07
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The ICMUB will have a participant in the regional finals of Ma Thèse en 180 secondes #MT180. Congrats to Elisa Chazeau for her selection! The event will take place at the Kursaal of Besançon, March 18th 18h. Voting is open to the public! Come UBFC - Université Bourgogne-Franche-Comté and support her!
The biological prevalence and functional relevance of an alternative nucleic acid structure referred to as i-motif #iM are fully described in this brand new review Trends in Genetics CNRS 🌍 CNRS Chimie @univbourgogne CNRS Centre-Est
Structural Optimization of Azacryptands for Targeting Three-Way DNA Junctions (David Monchaud and co-workers) Anton Granzhan 🇺🇦 Institut Curie David Monchaud @icmub CNRS Chimie #openaccess onlinelibrary.wiley.com/doi/10.1002/an…
Targeting DNA junctions for fighting against cancers! An @icmub work in collaboration with Paris, Toulouse and Brno (CZ). Congrats to all authors! @univbourgogne CNRS Chimie
An historical perspective on DNA interacting compounds used as anticancer agents, written by an @icmub @univbourgogne CNRS Chimie member in honour of Prof. Stephen Neidle UCL UCL School of Pharmacy @ucllifesciences
An ICMUB contribution aiming at deciphering the roles that a peculiar DNA structure known as G-quadruplex #G4 plays in a neurodegenerative disease (XDP) published in @NAR_Open 👍👍👍 CNRS 🌍 CNRS Chimie CNRS Centre-Est @univbourgogne
‼️highlight alert‼️ Thanks CNRS Chimie for highlighting this @icmub work done in collaboration with Anton Granzhan 🇺🇦 Institut Curie Sébastien Britton @IpbsToulouse Nicolas Chéron Chimie ENS and Lukas Trantirek CEITEC
#chimie ⚗️ #ResultatScientifique 📕 🔎 l Une nouvelle cible #thérapeutique prometteuse sur l’ADN de cellules #cancéreuses et des molécules capables de s'y attaquer de manière sélective. 🤝 @univbourgogne CNRS Centre-Est David Monchaud ➡️inc.cnrs.fr/fr/cnrsinfo/ci…
A free-flowing and spirited discussion on @icmub research related to DNA structure oddities (G-quadruplex, #G4) that may have a profound impact on our daily lives (aging and age-related diseases). Thanks to the CNRS (CNRS 🌍 CNRS Chimie CNRS Centre-Est) for this opportunity
Another beautiful collaboration between ICMUB and UTHealth Houston McGovern Med School which aims at deciphering the roles that G-quadruplex #G4 DNA and RNA play in human cells using chemical biology means. CNRS 🌍 CNRS Chimie @univbourgogne
In this STAR Protocols article, J. Mitteaux & D. Monchaud from @icmub describe in a step-by-step manner how to fish RNA G-quadruplex #G4 out from human cells using commercially available TASQs, either BioCyTASQ (sigmaaldrich.com/FR/en/product/…) or MultiTASQ (sigmaaldrich.com/FR/en/product/…)
In this new J. Am. Chem. Soc. article, a collaboration between ICMUB, Nanjing University, École polytechnique and Université Sorbonne Paris Nord report on CoRP-seq, a technique that allows for mapping RNA G-quadruplex #G4 transcriptome-wide in a faster, cheaper and simpler manner! 👉 doi.org/10.1021/jacs.5…
@icmub was associated to a consortium steered by CRCT-Oncopole to decipher how G-quadruplex #G4 RNA can be leveraged for mitochondrial translation-targeted therapy to fight against cancers Now in Nature Communications👍 CNRS Chimie CNRS Centre-Est @univbourgogne doi.org/10.1038/s41467…
ICMUB is proud to have been associated with the very 1st meeting on DNA/RNA junctions IMAJ#1 organized by David Monchaud.bsky.social and funded by CNRS Chimie (IRN). The meeting took place in Paris from 12 to 14 May, 2025 and was a real success! Great talks and enriching discussions!
A novel demonstration of the G-quadruplex #G4 unfolding properties of PhpC, a quite unique prototype of G4 unfolder (or molecular helicase) made in ICMUB In collaboration with Univ. Beira Interior and Western University 👉doi.org/10.1016/j.ijbi…
A fruitful collaboration between @icmub (FR) and IIT Gandhinagar (IN) supported by EMBO Fellows led to a novel strategy to fight against colorectal cancer, which relies on the pharmacomodulation of G-quadruplex #G4 found in miRNA. Now published in BMC Biology doi.org/10.1186/s12915…
An interview of D. Monchaud, CNRS 🌍 researcher @icmub now published Pour la Science to discuss about the results of Simon Elsässer and Puck Knipscheer recently published in Science 👉science.org/doi/10.1126/sc… 👉pourlascience.fr/sd/genetique/l… (sorry, in French only)
A novel collaboration between @icmub (FR) and Nanjing University (CN) which keeps on expanding the repertoire of biotechnological applications of G-quadruplex #G4, here to track undesired antibiotics in food. Now published in ACS Analytical Chemistry Journals 👉 doi.org/10.1021/acs.an…