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Publication - by Dr. Ya-Jen Chang's group 中央研究院 Academia Sinica Cell Reports

Publication-by Dr. Patrick CH Hsieh's research group 中央研究院 Academia Sinica Biomaterials The gut microbiota regulates acute foreign body reaction and tissue repair after biomaterial implantation. #GutMicrobiota #TissueRepair sciencedirect.com/science/articl…

Research group led by Dr. Che-Ming Jack Hu 中央研究院 Academia Sinica developed an innovative cell-derived biomaterial system for robust expansion of stem cells, which has significant therapeutic implication in regeneration medicine and tissue engineering. tinyurl.com/bdz43smf

Publication-by Dr. Mi-Hua Tao's research group 中央研究院 Academia Sinica A receptor-binding domain-based nanoparticle vaccine elicits durable neutralizing antibody responses against SARS-CoV-2 and variants of concern doi.org/10.1080/222217…

A new study from Prof. Patrick CH Hsieh 中央研究院 Academia Sinica has shown that ketone production in the heart links to dedifferentiation process and can allow for regeneration after injury. Circulation ahajournals.org/doi/full/10.11…

Incorporating polymer skeletons inside bacteria stops them from replicating but preserves essential cellular function. Scientists have dubbed them "cyborg cells" that are half living and half artificial... Tan Lab Jack Hu UC Davis College of Engineering Ching-Lung Hsu ow.ly/Ur0M50Msv6S

New research from Dr. Woan-Yuh Tarn’s group 中央研究院 Academia Sinica suggests that non-coding RNA HOTAIRM1 and RNA processing factor Y14 play crucial roles in DNA repair. Nucleic Acids Res RNA doi.org/10.1093/nar/gk… DOI: 10.1261/rna.079514.122

Researchers led by Dr. Yungling Lee & Dr. Ya-Jen Chang 中央研究院 Academia Sinica found neutrophil extracellular trap production and CCL4L2 expression influence corticosteroid response in asthma. Science Translational Medicine shorturl.at/bmnx7

Development of AAV-delivered broadly neutralizing anti-human ACE2 antibodies against SARS-CoV-2 variants #genetherapy #celltherapy dlvr.it/SvskCN

Research team in IBMS 中央研究院 Academia Sinica is developing broad-spectrum antiviral drugs to combat COVID-19 variants. They discovered the monoclonal antibody ch2H2, which effectively neutralized various COVID-19 variants. Molecular Therapy Article link: bit.ly/3S5kKZ5

Team led by Prof. Patrick CH Hsieh 中央研究院 Academia Sinica successfully restored and regenerated damaged hearts through the co-transplantation of human induced pluripotent stem cell (iPSC)-derived endothelial cells and cardiomyocytes. Circulation doi.org/10.1161/CIRCUL…

Dr. Patrick C.H. Hsieh’s team at the Institute of Biomedical Sciences 中央研究院 Academia Sinica uncovered a pivotal gut-heart axis in post-myocardial infarction (MI) cardiac repair. Nature Communications #cardiacrepair #cardioprotection nature.com/articles/s4146…

🔍 Dr. Yijuang Chern’s team Yijuang Chern 中央研究院 Academia Sinica demonstrates the critical role of microglial Galectin-3 in worsening tauopathy, like Alzheimer's disease. Journal of Clinical Investigation jci.org/articles/view/…

🧬 Dr. Ruey-Bing Yang’s team 中央研究院 Academia Sinica reveals SCUBE2's pivotal role in maintaining vascular integrity during inflammation. 💡 Deleting Scube2 = increased barrier dysfunction 💡 Overexpressing/upregulating SCUBE2 = protection #CardiovascularResearch doi.org/10.1093/cvr/cv…

🔬Publication - by Kevin Tsai Kevin Tsai and colleagues IBMS, Academia Sinica 中央研究院生醫所 Epitranscriptomic cytidine methylation of the hepatitis B viral RNA is essential for viral reverse transcription and particle production | PNAS pnas.org/doi/10.1073/pn…

Research collaboration between Kurt Yun Mou and Jack Hu 中央研究院 Academia Sinica developed a combinatorial probiotic that secretes oncolytic and immunomodulatory chimeric proteins for tumor eradication and anticancer immunity induction. The work was published Cell Reports Medicine.

Dr. Chien-Chang Chen's team 中央研究院 Academia Sinica identifies neurons in the thalamus (PVA) regulate sensory and emotional pain via distinct circuits, uncovering key mechanisms and potential targets for pain therapy. Study in Cell Reports sciencedirect.com/science/articl… #ChronicPain

Exciting first day of the 2nd Annual Symposium of Taiwan Circulation Research Society (TCRS)/2025 Stanford-Taiwan Symposium on Biomedical Advances 中央研究院 Academia Sinica IBMS, Academia Sinica 中央研究院生醫所! What an outstanding speaker lineup! 🤩🤩🤩 tcrs.org.tw/conference-202…

💊The Difference Between 'Sng' and 'Pain': Medical Neuroscience Advances to Precision Treatment Era 🔬Dr. Chih-Cheng Chen's team found a role for proprioceptors in sngception. Science Advances science.org/doi/10.1126/sc… #ChronicPain

🔬🧲 Published in Nature Communications, Dr. Jack Hu's team 中央研究院 Academia Sinica developed magnetic polymerized antigen presenting cells to enrich tumor-reactive T cells and identify neoantigens. #CancerImmunotherapy #Tcells #Neoantigen 📌 nature.com/articles/s4146…