Is the frequency of #lupus increasing? A #thread 🧵

Increasing Risk of Lupus Nephritis A population based study shows that LN in the US has increased in the last four decades and that LN patients have poorer outcomes with high rates of ESRD and mortality rates 6x that of the general population. bit.ly/3stuz51

Do you think ANA is being over utilized? Check out our virtual poster! Our population-based study shows 12% of all females and %6 of all males have been tested at least once in the past 20 years in our geographic region. #ACR22 Alain Sanchez, MD Alí Duarte, MD Cynthia Crowson

🎇Thanks to the CDC for highlighting the work of research fellow extraordinaire Gabriel Figueroa-Parra, MD, MSc Findings: 💥 10% of SLE patients and in long term options therapy 💥 Pericarditis, fibromyalgia, depression, h/o fragility fractures is associated with long term opioids. LUMEN💡

Just accepted in Arthritis & Rheumatology: Incidence, Prevalence, and Mortality of Lupus Nephritis: A Population-Based Study Over Four Decades—The Lupus Midwest Network (LUMEN) onlinelibrary.wiley.com/doi/abs/10.100…

I am very happy to share that I will be joining the PittRheum fellowship program next year!

LUMEN💡 Mehmet Hocaoglu, MD Cynthia Crowson

I am happy to share that our abstract on the polymyalgia rheumatica GWAS from UK Biobank and Finngen has been accepted as a poster presentation for the upcoming #ACR2023. Thank you to Chaz Hong MD PhD 🇺🇸 Drs. Perry and Mikdashi for their support!

Our rheumatology fellow Mehmet Hocaoglu, MD first-author publication in A&R showing ANA production is primarily determined by non-genetic factors independent of lupus genetic risk PittRheum Pitt Department of Pediatrics PittDeptofMed UPMC Physician Resources ACR_Journals acrjournals.onlinelibrary.wiley.com/doi/10.1002/ar…

Thank you for supporting our research! Arthritis Foundation. Our goal is to develop prediction models powered by machine learning/AI and find new drug targets for the prevention of rheumatoid arthritis.

NEW! Curious about how genetics influence autoimmune disease risk? Tune in & hear from Mehmet Hocaoglu, MD, who dives into the study of antinuclear antibody production using data from the All of Us Research Program → acr.tw/42d7QN2 ACR_Journals

See our recently published paper with Amr Sawalha, MD below!