In the Spotlight—
Unlocking the Role of Age-Related Changes to Fibroblasts in #PancreaticCancer , by Achinoam Isaacson, Debra Barki, and Scherz Shouval Lab.
aacrjournals.org/cancerres/arti…
Weizmann Institute

New review in the April 15 issue:
Exploiting Tertiary Lymphoid Structures to Stimulate Antitumor Immunity and Improve #Immunotherapy Efficacy, by Giulia Petroni et al.
bit.ly/3UbZoZ7
Università di Firenze

New in #CancerBiology from the April 15 issue:
Fibroblasts in the Aged Pancreas Drive #PancreaticCancer Progression, by Daniel Zabransky, Dr. Elizabeth Jaffee, Ashi_W et al.
bit.ly/4b4rIUj
Johns Hopkins Kimmel Cancer Center

The April 15 issue is online.
bit.ly/4dcXyQL

Now online in Cancer Research ! Our article on p38-mediated stromal inflammation + resistance in #PancreaticCancer & encompassing most of my PhD!👩🏽‍🔬
Huge thanks to our lab! 🤗🐁Nipun Merchant Nagaraj Nagathihalli, PhD Jash Datta, MD Sylvester Comprehensive Cancer Center Miller Medicine

Check it out:
aacrjournals.org/cancerres/arti…

Toasting a successful #AACR24 so far with Harmony Turk!

If you enjoyed the talk by Daniel Zabransky at #AACR24 during the Microenvironment session, be sure to read his recent paper on aged fibroblasts in #pancreaticcancer .
bit.ly/3VOimHX
AACR

Stop by Section 17 Board 18 (Abstract 5697) at #AACR24 to learn about this Cancer Research paper out today:
MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative #BreastCancer
aacrjournals.org/cancerres/arti…

Check it out - presented in the current #AACR24 poster session and online now in Cancer Research
Oncogene-driven non-small cell lung cancers in patients with a history of smoking lack smoking-induced mutations
aacrjournals.org/cancerres/arti…

Simultaneous publication in Cancer Research being presented now at #AACR24 !
Transfer learning reveals cancer-associated fibroblasts are associated with epithelial-mesenchymal transition and inflammation in cancer cells in pancreatic ductal adenocarcinoma
aacrjournals.org/cancerres/arti…

I always miss my dog while traveling, but at least I can still get a puppy at #AACR24 !

The Cancer Research Senior Editor Dr. Nelly Polyak Polyak Lab gave a great plenary talk at #AACR24 on drivers of age-related increase in breast tumorigenesis.

Presented this morning at #AACR24 by Huang Lab and Online First in Cancer Research:
Integration of pan-cancer cell line and single-cell transcriptomic profiles enables inference of therapeutic vulnerabilities in heterogeneous tumors
aacrjournals.org/cancerres/arti…

I’ve just landed in San Diego, and I’m looking forward to lots of great science over the next few days!

Productive Peer Review: Improving Science while Avoiding Pitfalls—
Cancer Research editor-in-chief Christine Iacobuzio-Donahue and Cancer Discovery editor Christine Lovly, MD, PhD will moderate this #AACR24 career development session on Monday, April 8, 5:30-7:00 PM. bit.ly/3QbFKvt Chris Iacobuzio

The April 1 issue is online.
bit.ly/4cHNj6r

In the Spotlight—
AKTing on R Loops Makes for an ATRactive Target in #OvarianCancer Therapy, by Vijayalalitha Ramanarayanan and Philipp Oberdoerffer.
aacrjournals.org/cancerres/arti…
Johns Hopkins Medicine

New in Translational #CancerBiology from the March 15 issue:
AKT1 interacts with DHX9 to Mitigate R Loop–Induced Replication Stress in #OvarianCancer , by Tzu-Ting Huang et al.
bit.ly/4cDRtfB
NCI Center for Cancer Research

In an National Cancer Institute funded study, OzgurSahinLab Medical University of South Carolina (MUSC) et al. found that targeting TACC3 overcomes resistance to trastuzumab emtansine (an antibody-drug conjugate) and induces immunogenic cancer cell death in preclinical models of #BreastCancer Cancer Research bit.ly/4cdnhIi.