New #preprint available. If you are interested in #epigenetics and how alterations in methylation impact gene expression in #COPD, how we can predict #diseaseregulators and design #screens just open this link biorxiv.org/content/10.110…👈👈

Researchers induced mass cell death in aggressive neuroblastoma tumours in mice, and they say the treatment could apply to other hard-to-treat cancers newscientist.com/article/231797…

Great to see this together and been able to share our recent story biorxiv.org/content/10.110… Result of a terrific collaboration with many groups, first and foremost HI-STEM - Cancer and Stem Cells in Heidelberg, and spearheded by Hamed Alborzinia and our PhD student notwitter Zhiyi Chen and Umut Yildiz.

New study from members of our consortia #spp2306 HI-STEM - Cancer and Stem Cells in Heidelberg José Pedro Friedmann Angeli Hamed Alborzinia identifying #selenocysteine uptake mechanism as a novel vulnerability in #neuroblastoma - check this out! #ferroptosis #celldeath #metabolism DFG public | @[email protected]

It's happening! First EMBO-Workshop on Ferroptosis 🥳🥳🥳 "FERROPTOSIS: When metabolism meets cell death 23–27 April 2023 | Seeon, Germany"🗻🚠🗻 interested in participating? register here for updates👇👇👇 coming-soon.embo.org/w23-19 EMBO Events The Conrad Lab Maria Fedorova

Very happy to see yu wei zhang PhD thesis MPI of Immunobiology & Epigenetics on the regulation of human dormant HSCs just online in Nature Cell Biology! Huge congrats Yu Wei! And HUGE thanks to all our collaborators :) nature.com/articles/s4155…

Highly recommended review about metabolism in HSCs by Keisuke and Claudia! Keisuke_Ito_Lab (Old)! Very happy to be part of the team :)))

🚨🚨Our mini-review is out🚨🚨 Congratulation to Thamara Nishida and Irina Ingold #notwitter for putting this together portlandpress.com/biochemsoctran… thank you James Murphy for the invitation to contribute to the special issue on cell death Portland Press #ferroptosis #Gpx4 #shortform🫠

Here is my take on the current state of the growing #ferroptosis field after the first 10 years. Freely available at Cell -- @columbia Columbia - Irving Institute for Cancer Dynamics CU Cancer Center Columbia University_Bio Enjoy! sciencedirect.com/science/articl…

Proud to share our latest work unveiling an unexpected link between vitamin K (VK) & #ferroptosis. FSP1 sustains a novel non-canonical VK cycle suppressing #ferroptosis and is the long sought-after warfarin-resistant VK reductase in the canonical VK cycle disq.us/t/49naz4i

🎉Extremely happy to share our review on the intrinsic and extrinsic factors regulating #PDAC subtype heterogeneity! Now at Trends in Cancer . Great time with Shiv K Singh & Lab, Ellen Puré and Lukas Klein putting this together 😀😀✍️cell.com/trends/cancer/…

📢📢Interested in #celldeath #ferroptosis #selenocysteine, here is Ancély F dos Santos Thamara Nishida #AhmedFazeli review now published Trends Cell Biology thanks to @i_carnevalebfor for the invitation and reviewers for great suggestions Ferroptosis (SPP 2306) @RVZ_Wuerzburg📢📢 authors.elsevier.com/a/1h7Xs_LvCM5J…

🚨🚨🚨🚨🚨🚨🚨🚨🚨🚨🚨🚨🚨🚨🚨 We have two openings in a joint project with Vivek Venkataramani as part of the Ferroptosis (SPP 2306) If you are interested in #ferroptosis #hematological malignancies #celldeath. See description below 🙏🙏retweets (re-xs) are highly appreciated 🙏🙏

🔬 Spread the word🛰️We're seeking a talented postdoc passionate about #CRISPR screens, #redoxbiology, and synthetic lethal interactions. If you're driven to unravel molecular complexities and explore gene interactions as potential anticancer strateges, get in touch! #PostdocJobs

Scientists of Universität Würzburg #UniWürzburg, DKFZ and HI-STEM - Cancer and Stem Cells in Heidelberg have found that a precursor of cholesterol protects #cancer cells from cell death and makes them aggressive. The results opens up exciting prospects for further improving the treatment of cancer. nature ➡️ t1p.de/o4h24

new out in Nature, two complementary ferroptosis papers nature.com/articles/s4158… and nature.com/articles/s4158…

Delighted to be part of this awesome study! Huge congrats to José Pedro Friedmann Angeli lab and all co-authors. A big thanks to the HI-STEM - Cancer and Stem Cells in Heidelberg lab and colleagues at DKFZ. 🎉🎉🎉🥳

The discovery that an evolutionarily conserved molecule used to make cholesterol also acts as a defence against cell-death might lead to new ways to treat cancer and other clinical conditions go.nature.com/3HGJwbl

Thank you, Cancer Discovery and Elizabeth McKenna, for highlighting our recent work showing that 7-DHC protects cells from #ferroptosis 🤗 @RVZ_Wuerzburg DFG public | @[email protected] Ferroptosis (SPP 2306)

biorxiv.org/content/10.110… Thrilled to present our manuscript identifying an alternative selenocysteine (Sec) metabolism pathway! 🚀 PRDX6, not just SCLY, can mediate Sec metabolization, playing a key role in ferroptosis response. Congrats to all authors!#Metabolism #Ferroptosis