Our new paper in Nature Genetics!! Single-cell deconvolution of various somatic mutations including mCAs, loss of Y, and mt-heteroplasmy. nature.com/articles/s4158…

Our Japanese multi-omic immune cell atlas is out in Nature Genetics! We projected omics layers — from germline/somatic mutations to metagenomics — into single-cell space to uncover dynamic immune regulation. nature.com/articles/s4158…

Single-cell ＆dynamic eQTL PBMC of Japanese PBMC🧬🩸🖥️. Somatic mutations (mosaic chromosomal alteration; mCA, loss of Y; LOY, mitochondria heteroplasmy) projected to single cell resolution by Ryuya Edahiro Go SATO & team🤼. Now Nature Genetics ㊗️🎉 nature.com/articles/s4158…

Excited to share our whole-genome sequencing study on psoriasis out in Cell Genomics! Looking into rare and structural variants highlighted the disease genetics that conventional GWASs have overlooked. dlvr.it/TMdf1X

WGS structural & rare variant analysis of psoriasis vulgaris identified IFNLR1 3kb deletion SV & risk RV at cercam fol by long-read seq, skin spatial transcriptome, knockout mouse with imiquimod psoriasis model. Lead by Kyuto Sonehara in Cell Genomics🎉 cell.com/cell-genomics/… #WGS

Our Platforms & Finalists #ASHG2025🎉🧬 Kyuto Sonehara SV & RV psoriasis risk by WGS: CERCAM as novel risk gene Sugahara K. East Asian GWAS of serum immunoglobulin & subclass for humoral immunity Go SATO Male genetic regulation of germline & somatic Y chr variation shape T2D risk