Personalized molecular signatures of insulin resistance and type 2 diabetes. Great collaboration with Anna Krook & atul deshmukh and teams! A comprehensive clinically focused study of insulin signaling in skeletal muscle. 💪 Online Cell sciencedirect.com/science/articl…

NOW HIRING! We're looking for an assistant professor/investigator to lead our metabolism-focused research program Morgridge Metabolism through this joint tenure track position with UW–Madison UW Biomolecular Chemistry. Ready to take the next step in your career? Join our team! morgridge.org/job-posting/as…

Congratulations Dudley Lamming Lab ! So well deserved!! 👏🏻👏🏻👏🏻

RESEARCH | Dylan Duerre, Andrea Galmozzi et al. (UW–Madison): Inhibition of haem synthesis is shown to lead to the accumulation of branched-chain amino acids in the brown adipose tissue of mice, which impairs #thermogenesis 🐭🌡️ nature.com/articles/s4225…

A nitroalkene derivative of salicylate, SANA, induces creatine-dependent thermogenesis and promotes weight loss go.nature.com/3SZcRDD

A brief guide to statistical analysis of grouped data in preclinical research go.nature.com/4ncNcVJ

Dr. Yoneshiro beautifully summarizes in Trends in Endocrinology & Metabolism our recent work doi.org/10.1038/s42255…! Thank you! Branched metabolic pathways to generate heme and heat: Trends in Endocrinology & Metabolism cell.com/trends/endocri…

nature.com/articles/s4225…

New paper from Jakub Bunk and Mina Ersin in our lab: CKB is the key creatine kinase driving UCP1-independent #thermogenesis in beige fat via the futile creatine cycle (FCC). doi.org/10.1016/j.molm… Rosalind & Morris Goodman Cancer Institute McGill Biochemistry Molecular Metabolism

Stay cool! biorxiv.org/content/10.110…

Please share! Registration for our Frontiers in Metabolism Meeting closes one month from today. Don't miss your chance to join us in Madison in September with our fantastic group of speakers. Morgridge Institute Discovery Building morgridge.org/research/metab…

2025 Roll & Stroll for Pancreas Cancer - Campaign give.wiscmedicine.org/event/2025-rol…

FINAL 2 WEEKS! The deadline to register, submit your abstract, and apply for a travel award is August 1st for the #AdiposeBiology Conference, happening in Montreal in just 1 MONTH. Secure your spot now at adiposebiology.com! #ABC2025 Sable Systems International 🐭🐀🧝🏼‍♀️ Lawrence Kazak Jacqueline Beaudry Hoon-Ki Sung Lab

Type 2 diabetes is often considered a protein misfolding disease. But where are these toxic proteins found? 🤔 🚨In new work out today in Nature Metabolism, we show that mitochondrial protein misfolding (yes mitos🤯) leads to beta cell damage in T2D. 🚨 nature.com/articles/s4225… 1/n

Over 7 billion...yes BILLION doses of Covid mRNA vaccines have been given So you can hardly keep calling it experimental. And based on anti vaxxer propaganda about how dangerous it is, we should have seen most of the world's population wiped out by now. Didn't happen.

If you or someone you know wants to support our lab and get a nice tax break while you’re at it, donations can be accepted here: giveto.ucsd.edu/giving/home/gi…

I cannot stress this enough: pairing a 4% funding line with the largest cut in NCI history will devastate the future of cancer research - and patients. We would be turning our backs on decades of progress.

This new preprint was designed so poorly that it provides absolutely no proof that mRNA vaccines caused cancer/other diseases. It compared 10 (!) handpicked sick patients to 803 healthy patients. And behold, they show different RNA expression profiles. Because they were sick.

Selective remodelling of the adipose niche in obesity and weight loss | Nature nature.com/articles/s4158…

The proteomic blueprint of #aging across 13 human tissues cell.com/cell/abstract/…