Congratulations Wouter Smagghe, well done 👏 Welcome to the Functional Interactomics group @PSB_VIB VIB UGent Wetenschappen

Enjoy the Xmas holidays and looking forward to 2021 🥂 @PSB_VIB VIB UGent UGent Wetenschappen #SocialDistancing #ChristmasTree #ChristmasLlama #Christmas

Interesting talk by Geert De Jaeger (Geert De Jaeger's lab @dejaegerlab.bsky.social) in the #EMBOtor workshop about the mapping of a #proteome-wide #SnRK1 signaling network in #Arabidopsis. This amazing work was developed by Jelle Van Leene, Astrid Gadeyne and other members from De Jaeger lab.

Check out our last preprint and find more about the AP interactions in Arabidopsis. With 蕭蔚 (Wei Siao) @DanielVanDamme1, Geert De Jaeger's lab @dejaegerlab.bsky.social, Kris Gevaert and Christa Testerink VIB @PSB_VIB 🌱🌱🌱🌱

Check out our preprint where we develop a straightforward (SYMPL) cloning toolbox to visualize #PPI and #kinase activity in planta based on #phase #separation. It enables sensitive detection at high signal/noise ratio in different subcellular compartments biorxiv.org/content/10.110…

including our in vivo SnRK1 kinase reporter :-)

New Article / Resource: "Mapping of the plant SnRK1 kinase signalling network reveals a key regulatory role for the class II T6P synthase-like proteins" rdcu.be/cZH3j Phosphoproteomics, affinity purification + Mass Spec, proximity labelling, crosslinking + MS, etc...

Colorful but expensive. Check out our preprint: SnRK1 inhibits anthocyanin biosynthesis through both transcriptional regulation and direct phosphorylation and dissociation of the MYB/bHLH/TTG1 MBW complex. biorxiv.org/content/10.110…

Another nice collaboration with Geert De Jaeger's lab @dejaegerlab.bsky.social, Ildoo Hwang, and Wim van den Ende KU Leuven Plant Institute.

Dipesh's paper is now published, and selected as a NAR Breakthrough Article. Congrats Dipesh (the champagne is in the fridge)! FANCC–FANCE–FANCF complex is evolutionarily conserved and regulates meiotic recombination academic.oup.com/nar/advance-ar…

Phase separation-based visualization of protein­–protein interactions and kinase activities in plants (Alaeddine Safi, Wouter Smagghe, Amanda Gonçalves, Qing Wang, Ke Xu, et. al.) buff.ly/441X62C Alaeddine Safi @wsmagghe ASPB #PlantSci

Check out our latest work in Molecular & Cellular Proteomics where we mapped a #nitrogen specific protein interaction network around the #SnRK1 and #TOR kinases in #Arabidopsis, highlighting a key role for the #ER as a hub for integration of #nutrient levels doi.org/10.1016/j.mcpr…