Smooth Muscle Hamartoma 👶👶🔬✏️ ✔️Rare ✔️Congenital lesion ✔️flesh colored plaque ✔️Composed of randomly arranged bundles of mature smooth muscle in the dermis ✔️overlying epidermis may show hyperkeratosis, acanthosis and hyperpigmentation #pathology #dermpath #PediPath

LANGERHANS CELL SARCOMA: Rare tumor of dendritic family often in dermis/subcutis. Sheets of bizarre pleomorphic/epithelioid cells. Rare dx not to forget about! (+) Langerin, S100, CD1a. #bstpath Jerad Gardner, MD @histiocytosisX Steven Billings, MD Scott Lauer, MD Rajiv M. Patel, M.D.

The colorectal polyps in juvenile polyposis (JP) feature striking multilobulation. This patient's polyps also had low-grade dysplasia, which cannot be distinguished from sporadic adenomas in superficial samples. JP patients are at risk for colon adenocarcinomas. #umiamipath

This epithelioid malignant peripheral nerve sheath tumor shows loss of INI1/SMARCB1, a feature of this type of neoplasm. innovativesciencepress.com

Hu S, Alpert L, Cates JMM, Gonzalez RS; Rare GIST Risk Stratification Group. Gastrointestinal stromal tumors (GISTs) arising in uncommon locations: clinicopathologic features and risk assessment of esophageal, colonic, and appendiceal GISTs. Mod Pathol. 2022 Apr;35(4):554-563.

Back to some basics. Leiomyosarcomas are amongst the sarcoma types that spread to lymph nodes, a phenomenon that is interesting to see.

👑 Leukocytoclastic vasculitis — one to rule them all, and in the vessels bind them 💥🧙‍♂️ #pathology #pathologists #pathTwitter #dermpath #dermatology #dermtwitter

Spitzoid melanoma Atypical lesion showing large, atypical melanocytes, often with abundant cytoplasm and large, vesicular nuclei #path #pathology #dermpath #medicine

Dermatofibrosarcoma protuberans survival. Molecular testing can be informative! Yeung MCF, et al. Comprehensive Clinicopathological and Multiomics Characterization of Dermatofibrosarcoma Protuberans Revealed PDGFD Fusion as Distinct Molecular Subtype With Better Survival. Mod

my.uscap.org/app/program/8Z… During this hands-on case-based course, we'll review the newest diagnostic & classification updates of tubular GI neoplasms, with changes coming up in the new WHO blue book to be published in early 2026, with some of its actual editors & authors! #pathX

75-year-old male with a 4 cm mass in the lower pole of the right kidney. CA9 diffusely positive = CCRCC with a cute morphological appearance. #gupath GU Pathology Society (GUPS) International Society of Urological Pathology

Foot, 30y #pathology #patologia #pathoutpic #bstpath #dermpath

Not my typical #gupath #gynpath post but an interesting one for trainees! Colon biopsy for GI bleed, clinical concern for IBD. #pathboards

Erythematous macules on trunk of 30 yo man. Your diagnosis? Answer & video here: youtube.com/watch?v=F5PcnZ… You must have high index of suspicion for this in #dermpath...most cases won't be so classic! #pathology #pathologists #pathTwitter #dermatology #dermatologia #dermtwitter

Core biopsy of inguinal lymph node from adult female. What was the primary tumour? #pathology #PathX

20 yo M w/ 5 cm lytic bone lesion in proximal tibia metaphysis, sharply demarcated w/ sclerotic rim. Answer ✅ youtu.be/LIY3jatGjv4?si… Digital slide: kikoxp.com/posts/4606. #BSTpath #radpathmatch #radiology #pathology #pathTwitter #orthotwitter

Elderly female with enlarged inguinal lymph node. Known history of _____? #PathTwitter #PathX #pathology

Breast biopsy for distortion.

30 yo F with intramuscular thigh mass. No connection to bone on imaging. Answer ✅ youtube.com/watch?v=kb737f… WSI digital slide: kikoxp.com/posts/5130. #BSTpath #pathologists #pathology #pathTwitter