Emile Roberts
@emileroberts97
I study mitosis @Dunn_School @UniofOxford
ID: 1518903541716459522
26-04-2022 10:43:36
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Really excited to finally get this story out there that Dan Hayward and I have been working on! New insights into the basis of MPS1 recruitment and error correction during mitosis. biorxiv.org/content/10.110…
New paper by the Gruneberg lab in Current Biology, led by Dan Hayward and Emile Roberts, changes the view of how MPS1 initiates the Spindle Assembly Checkpoint. Read more on our website ⬇️ (Written by Isaac Siu-Shing Wong, edited by Bella Maudlin) path.ox.ac.uk/news/changing-…
Finally, our paper is online Journal of Cell Biology !! "PP6 regulation of Aurora A–TPX2 limits NDC80 phosphorylation and mitotic spindle size" rupress.org/jcb/article/22…
.Tomogotchi, PhD, Kowalczyk, Skylakakis, Barr et al. Department of Biochemistry at Oxford University Dunn_School (now @DunnSchool.bsky.social) show that PP6 limits the activity of Aurora A toward the #kinetochore protein NDC80, thereby regulating spindle size and chromosome segregation. bit.ly/3ZC3FH3 #mitosis #celldivision
PP6 regulation of Aurora A–TPX2 limits NDC80 phosphorylation and mitotic spindle size, say Tomoaki Sobajima Tomogotchi, PhD, Katarzyna M. Kowalczyk, Stefanos Skylakakis, Francis Barr et al. Department of Biochemistry at Oxford University bit.ly/3ZC3FH3 Emile Roberts Dan Hayward #mitosis #kinetochores
Excited to share my 1st paper along with Bridget Watson Tiffany Taylor edze westra Sylvain Gandon and David McLeod academic.oup.com/ismej/article/… where we asked “when would using a defence system (CRISPR-Cas) be selectively advantageous over mutations that block phage binding?” 1/10