Epigenetics Update - A multimodal cross-species comparison of pancreas development go.nature.com/4nhBWWQ #Epigenetics #Chromatin #Pancrease #Multiomics --- High-resolution insights without cell sorting; epigenometech.com

“The only way of discovering the limits of the possible is to venture a little way past them into the impossible.” ― Arthur C. Clarke

Calcifying planktonic organisms—coccolithophores, foraminifers, and shelled pteropods—are the linchpins of the marine carbonate cycle and key regulators of atmospheric carbon dioxide. In a new #ScienceReview, researchers analyze which of their functional traits make them so

Scientists long thought the plant cell wall to be dead, but it's an active, even chatty participant in cellular growth, reproduction and responses to infection go.nature.com/4quhVPF

Pathogens accelerate features of human aging: A review of molecular mechanisms sciencedirect.com/science/articl…

The prognosis of liver disease depends on the extent of fibrosis, which is usually staged with the use of liver biopsy. The limitations of biopsy have led to the development of noninvasive tests, which Drs. Laurent Castera, Mary E. Rinella, and Emmanuel A. Tsochatzis review.

Goodbye Comet Lemmon. See you again in 1,155 years. ☄

Fat storage in the body relies on specialized structures called lipid droplets. In a new Science study, researchers identified the microprotein adipogenin as a regulator of adipocyte lipid droplet size, revealing a key mechanism in lipid homeostasis. Learn more in this week's

Chamonix-Mont-Blanc

Genomic and transcriptomic analysis of samples from patients with multiple myeloma, followed by in vitro validation, indicate mechanisms of antigen escape in response to GPRC5D T cell engager talquetamab, including biallelic deletions, small nucleotide variants and

#Obesity prevalence among US adults more than doubled from 19.3% in 1990 to 42.5% in 2022 and is projected to reach nearly 47% by 2035, with sharper increases among younger adults and persistent differences across states, sex, and race and ethnicity. ja.ma/4t2Pny7

An update to the Hallmarks of Cancer framework for understanding (and researching) what causes human cancers. spkl.io/6010Aqwbi Douglas Hanahan Cell

An analysis of twin cohort data suggests that human life span is far more heritable than previously believed. The findings of the analysis in Science show that once deaths from external factors, such as accidents or infectious disease, are accounted for, genetics may explain

Researchers studied blood-based metabolome of over 23,000 individuals from 10 ethnically diverse cohorts. They identified 235 metabolites associated with future risk of T2D. By integrating genetic and modifiable lifestyle factors, their findings provide insights into T2D

#Obesity prevalence among US adults more than doubled from 19.3% in 1990 to 42.5% in 2022 and is projected to reach nearly 47% by 2035, with sharper increases among younger adults and persistent differences across states, sex, and race and ethnicity. ja.ma/4akLzRv

Moderate consumption of caffeinated coffee or tea was linked to reduced #dementia risk and modest improvements in cognitive outcomes; no benefit was seen for decaffeinated coffee in an observational study of US adults. bit.ly/4amtd1c

Higher intake of caffeinated coffee or tea was associated with a lower risk of #dementia and modestly improved #cognitive function, with maximal benefit seen at moderate consumption levels. 🎥 Watch the video and read the full study: ja.ma/4anXb4Z

#Type1Diabetes affects approximately 2 million people in the US and 8.4 million people worldwide. 🔗 Learn more about the diagnosis and treatment of type 1 diabetes in this JAMA Review: ja.ma/46UF1a2

Nature research paper: A disease model resource reveals core principles of tissue-specific cancer evolution go.nature.com/4cIrt5i