Truly a sad day for all of us in the myeloma world.. Jack was a force in our fight against #mmsm.. RIP Jack! We miss you and love you!

Perhaps the best figure I've found supporting the use of Dara+Len maintenance after ASCT among those receiving DaraVRd. Even among MRD- patients, PFS looks better for DR vs R. Still not sure it's worth adding for everyone, but I'm more supportive of it. rdcu.be/dPFo2

15.6m US adults reported at least one potentially liver toxic botanical supplement w/in 30 days - turmeric was most frequently reported, followed in order by green tea, ashwagandha, Garcinia cambogia, red yeast rice, and black cohosh products. ☹️ jamanetwork.com/journals/jaman…

One [marijuana] joint a day increases the risk of head and neck cancer by 3.5-5%. jamanetwork.com/journals/jamao…

Can someone tell Robert F. Kennedy Jr the truth? cdc.gov/mmwr/volumes/7…

I’d prescribe SGLT2 inhibitors over chronic doxycycline in a heartbeat for patients with AL amyloidosis with cardiac involvement… Great work by Lang Raj Chakraborty Suzanne Lentzsch, MD, PhD et al! Hopefully positive prospective studies with this to come 🤞🏼

Clearly defines risk of CRS and ICANs in the first two weeks. No need to have patients stick around for a month closer to treatment centers and impose driving restrictions - for what? Thanks you Dr Nausheen Ahmed MD Saurabh Chhabra #mmsm

If the U.S. government wants to get serious about encouraging people to eat beans, it should offer workshops and online videos on delicious, easy ways to cook them nytimes.com/2024/08/12/opi…

What’s going on? Observation: the ER is now 4 or 5 times the size than when I worked there. But the number of true inpatient beds hasn’t increased proportionately. Hospitals can charge you for an inpatient room in the overflow unit. 5/9

I wonder if this push for lower doses of steroids would apply for #CRS in #myeloma #mmsm ascopubs.org/doi/10.1200/JC…

Did you know that the prescribing insert with Elranatamab includes pulmonary embolism but this did not occur with Teclistamab? #mmsm

MGUS + "x" = MGCS! + neuropathy+VEGF = POEMS + neutrophilic urticaria = Schnitzler + cutaneous mucinosis = Scleromyxedema + ataxic neuropathy+opthalmoplegia= CANOMAD + angioedema = C1 inhibitor deficiency + bleeding = aVWD + erythrocytosis+pulm shunting+telangiectasias = TEMPI

Hot off Press: Safety and Efficacy of #CART in #RRMM w sec #AL #Amyloidosis led by resident Cleveland Clinic ➡️Responses were rapid and deep ➡️No excessive or ⬆️Gr CRS ➡️Presence of amyloid should not be🛑🚧 CART pubmed.ncbi.nlm.nih.gov/39189919/ #mmsm #MedTwitter #UnmetNeed eJHaem Journal

Rep. John Garamendi announces he has multiple myeloma, will continue working through treatment msn.com/en-us/health/o… With a good myeloma specialist helping you pick the right trtmt plan, normal life can go on despite having myeloma.

In addition to steroids & 5HT3i, olanzapine should be considered as one of the standards of care to reduce chemotherapy-induced nausea and vomiting among patients receiving moderately emtogenic chemotherapy. #mmsm ncbi.nlm.nih.gov/pmc/articles/P…

It takes >3-4 weeks of steroids (@ any dose >5 mg pred/d) to pose risk of adrenal insufficiency – Hence, Endocrine Society Guideline says short-term glucocorticoid therapy of <3-4 wks, irrespective of dose, DOES NOT require GC tapering buff.ly/4gggMq6

Mass spectrometry is one of the most sensitive ways for detecting monoclonal protein in the peripheral blood. Similar to how there are different ways of detecting MRD in bone marrow (next generation sequencing or flow cytometry), there are different types of mass spec platforms

Lower-Intensity Talquetamab Dose Shows Potential in Multiple Myeloma targetedonc.com/view/lower-int… via @targetedonc Lower dose equates with lower toxicity and less T-cell exhaustion. Efficacy was maintained. We don't always need MTD. Let's please go for MED (minimal effective dose).

Denosumab $24,528 isn't worth it in patients with good renal function. Need our guidelines to go with the data (Larocca, Blood, 2013, PMID 23974194) and not Novartis marketing (PMID 22498739) - no bisphosphonate at all if #myeloma is in control. #mmsm pubmed.ncbi.nlm.nih.gov/39207867/

Does the serum free light chain assay matter? Here's a good comparison of Freelite vs Sebia showing equivalence; I bet we won't see this with Diazyme. #mmsm pubmed.ncbi.nlm.nih.gov/39206639/