Interesting #gupath case: poorly differentiated carcinoma w/squamous features involving the bladder - note the squamous component in the deep portion of low mag pic, more prominent in the high mag H&E and GATA-3 stain in the residual predominantly denuded urothelial surface 1/3

To summarize 2020 in an H&E image. #pathology #pathologists #PathArt MPathy Art/Mary Landau I Heart Histo Rutgers RWJMS Pathology

Great example of the exception to the "tightly packed small round glands favors cancer" - this doesn't look terribly infiltrative (still rounded), but depending on how the needle went through it could be challenging. Higher power very typical of post-atrophic hyperplasia #gupath

Plasmacytoid urothelial carcinoma (GATA3, CK7 and p40 positive) #pathology #pathologists #GUpath #pathboards Rutgers RWJMS Pathology

Marked nuclear atypia, pleomorphism, and frequent mitoses are characteristic of this tumor. Anaplastic spermatocytic tumor can be challenging to diagnose and could be. mistaken. for malignancy. The key lies in identifying all cell types. CD117+/OCT4- proves it #urology #GUpath

Something I learned from Jerad Gardner, MD. Gout crystals can be visualized under polarization on unstained FFPE slide, without red compensator filter. Coverslip is not necessary, but it looks better with one. #pathology #pathologists #pathboards Rutgers RWJMS Pathology

We are pleased to announce Dr. Isaac Y. Kim as our new Chair of Urology. Welcome, Dr. Kim! bit.ly/3huC5s5 Yale New Haven Hosp Yale School of Medicine Smilow Cancer Hospital Yale Cancer Center

This micropapillary urothelial carcinoma spread to the duodenum. Nasty nasty tumor.

Prostate biopsy with perivascular amyloid deposition. Don't forget to look beyond the glands! #pathology #pathologists #GUpath #pathboards

Morphologic manifestations of Regression in Clear Cell Renal Cell Carcinoma - Cell drop out - Edema - Fibrosis/sclerosis - Vascular prominence #kidneycancer #KidneyWk #gupath

Morphologic Manifestations of BENIGN #prostate tissue with profound treatment (radiation☢️) effect: - Dense eosinophilic cytoplasm - Peri-glandular fibrosis - Multi-layered cells with reactive nuclear & nucleolar atypia

Nice example of the rare Inverted #urothelial papilloma arising from prostatic #urethra, incidentally encountered on radical prostatectomy. PMID: 16861968 by Samson W. Fine, MD #GUPath

Rare encounter of lymphovascular invasion of #prostate cancer in biopsy. #GUPath

Benign Prostatic Tissue with Radiation Therapy Effect #gupath #prostate Learn more here▶️kikoxp.com/posts/19869

Perineural Involvement by benign prostatic glands 🚨may mimic #prostatecancer kikoxp.com/posts/20099 #gupath

#GUPath times two ✌️ Exquisitely rare nephroblastoma (Wilms’ tumor) arising from a testicular germ cell tumor.

May is #bladdercancerawarenessmonth - important to recognize lesions which mimic #bladdercancer Nephrogenic metaplasia/adenoma: - various architectures (papillary, tubular/glandular, vascular-like...) - cuboidal to hobnail nuclear features - prominence of basement membrane

May 2023 is #bladdercancerawarenessmonth Urothelial carcinoma can invade the prostate, mimic high grade #prostatecancer & occasionally be sampled on needle biopsy (see PICS) #gupath

For our 2023 #pathology trainees, remember this #GUPath adage👇 “Not all renal tumors with clear cells are clear cell renal cell carcinoma” … spot on in this molecular era! 👇Below are DDX for Clear cell #RCC including #renal tumors with some degree of cytoplasmic clearing🔬

Great to catch up with ⁦Evita Sadimin⁩ during #KCRS2024. “It’s all about negative margins.” ⁦Genitourinary Cancer Research Team @CityofHope⁩ ⁦The James⁩ ⁦Ohio State Wexner Medical Center Urology Dept.⁩