Our new paper on “p38 MAPK and glucocorticoid receptor crosstalk in bronchial epithelial cells” has now been published in Journal@of Molecular Medicine. Enjoy link.springer.com/epdf/10.1007/s…

Some more interesting work on Alveolar macrophage phenotype in COPD from our group. This time “Effects of corticosteroids on COPD lung macrophage phenotype and function” portlandpress.com/clinsci/articl…

Very topical work from our group here on being overweight with COPD and potential increased risk to COVID-19. See link for paper onlinelibrary.wiley.com/doi/abs/10.100… #Covid_19 #COPD

New study by Andrew Higham and Dave Singh - Increased ACE2 Expression in the Bronchial Epithelium of COPD Patients who are Overweight doi.org/10.1002/oby.22… #research #COVID19 The University of Manchester News

Out now! An adventure onto Helvellyn with @HayekTom John Muir Trust to talk managing visitors, Nuttall bagging, iconic views and why the fell means so much to so many. podbean.com/media/share/pb…

Assessment of bacterial exposure on phagocytic capability and surface marker expression of sputum macrophages and neutrophils in COPD patients onlinelibrary.wiley.com/doi/full/10.11…

Raising a glass after a morning trip up Hellvelyn on our much needed break to Watermillock on the edge of Ullswater. Where else in the world do you need to go? #LakesMoment

More great representation of the group at #ERSCongress, this time from Gus Beech talking about stability of sputum eosinophil counts in COPD.

While blood eosinophil count is the biomarker used in clinical practice to enable selective use of ICS in COPD, there is a complex interacting network involving the microbiome, airway inflammation and ICS that decides the clinical outcome in individuals bit.ly/3P1Jmjx

Fascinating new paper from Manchester BRC’s COPD research team which evidences the science behind the COPD treatment guidelines on the use of steroid inhalers 👇 #WorldCOPDDay

Unusual carbon build-up found in lungs of COPD patients sciencedaily.com/releases/2025/…

Scientists find unusual build-up of soot-like particles in lung cells of COPD patients manchester.ac.uk/about/news/sci…

Scientists find unusual build-up of soot-like particles in lung cells of #COPD patients & these cells grow abnormally large and cause inflammation, according to study by The University of Manchester published by ERS publications ERS European Lung Foundation tiny.cc/ybnm001

Read the full study in ERJ Open Research: publications.ersnet.org/content/erjor/…

Thanks to all the team for the hard work on our interesting paper showing unusual build-up of soot-like particles in lung cells of #COPD patients. The University of Manchester ERS publications NIHR Manchester Biomedical Research Centre Alveolar macrophage carbon is associated with COPD severity publications.ersnet.org/content/erjor/…

📰 Scientists from Manchester BRC's Respiratory Medicine Theme have found an unusual build-up of soot-like carbon deposits in lung cells of COPD patients. As a result, cells grow abnormally large and cause inflammation. 🔗manchesterbrc.nihr.ac.uk/news-and-event…

The research was led by Dr James Baker and Simon Lea from UoM Biology, Medicine and Health, with funding from Manchester BRC. They found that the average amount of carbon was more than three times greater in alveolar macrophage cells from COPD patients compared to smokers.