An incredibly fascinating lecture from Jack Szosta on the origin of life. 👇 youtu.be/ZLzyco3Q_Rg

Very interesting work!

Happy to share our new automated workflow for BioID and related proximity labelling approaches. Developed by Therese Dau and Emilio Cirri from the core facility #proteomics Leibniz-Institut für Alternsforschung (FLI) 👇biorxiv.org/content/10.110…

What are the factors influencing the evolution of #sperm length? We investigated sperm length evolution in relation to body mass across #tetrapods by applying a novel statistical framework: Pareto Optimality. (1/5) biorxiv.org/content/10.110…. @KocillariLoren @PilastroAndrea

Very happy to share our latest Nature Communications publication on age induced IFNγ-Stat1 axis activation in intestinal stem cells, leading to cell composition changes in epithelium and immune cells. 👨🏻‍💻 rdcu.be/dntJm

New work from the lab Nature Aging! 🌱🌱 We asked whether the ability of plants to suppress pathological protein aggregation can be applied into human cell and animal models to delay or even prevent neurodegenerative diseases nature.com/articles/s4358…

💡Our new pre-print is out! Here we analyze how Ubiquitin remodel the aging brain. 💡 We show that ubiquiting changes are particularly well conserved across species and highlight the role of proteasome activity in determining their levels. biorxiv.org/content/10.110…

Very happy to share our preprint that further confirms changes in ubiquitination during aging in C. elegans biorxiv.org/content/10.110…

Our updated study on killifish brain aging reveals a widespread reduction in proteins rich in basic amino acids. 📚🔬 No direct link to impaired proteasome or mRNA regulation—instead, abnormal translation pausing triggers an independent proteome overhaul. biorxiv.org/content/10.110…

Ten months ago, we launched the Vesuvius Challenge to solve the ancient problem of the Herculaneum Papyri, a library of scrolls that were flash-fried by the eruption of Mount Vesuvius in 79 AD. Today we are overjoyed to announce that our crazy project has succeeded. After 2000

OMG! This is truly next level!

Anthropocene

So sad to hear that.. Such a great scientist and philosopher!

This is such an incredible study! cell.com/cell/fulltext/…

In a new preprint from my lab Leibniz-Institut für Alternsforschung (FLI) we found that polyamines sustain the regeneration of the intestinal epithelium in old mice 👇biorxiv.org/content/10.110…

#Genome of #Greenland #shark #decoded ‼️ An international team of #scientists, including Steve Hoffmann and Alessandro Cellerino from the Leibniz-Institut für Alternsforschung (FLI), has mapped this Shark’s genome. 👉More information: bit.ly/4gkAGA8 👉bit.ly/3B0csek

For those interted in lysosome biology: there is a now a full brain lysosomal protome atlas! + New interesting insight! 🤫

Job Alert. We have 6-year funded positions for a postdoc and bioinformatician to join our European Research Council (ERC) #BATPROTECT project. Topics include genome assembly, annotation, comparative genomics & transcriptomics and more. Pls RT. tbg.senckenberg.de/hillerlab/jobs/