Congratulations to Jen Q Pan and team at the Stanley Center and Broad Institute for conducting the first ever base editing scan of a voltage-gated sodium channel. Super fun collaboration! #ionchannels #scn2a #epilepsy doi.org/10.1016/j.celr…

VIP interneuron impairment promotes in vivo circuit dysfunction and autism-related behaviors in Dravet syndrome dlvr.it/Sqc7Cn

𝗗𝗼 𝘆𝗼𝘂 𝗸𝗻𝗼𝘄 𝘄𝗵𝗮𝘁 𝗔𝘂𝘁𝗼𝗺𝗮𝘁𝗲𝗱 #𝗣𝗮𝘁𝗰𝗵𝗖𝗹𝗮𝗺𝗽 𝗰𝗮𝗻 𝗱𝗼 𝗳𝗼𝗿 𝘆𝗼𝘂𝗿 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵? 💡Join us on July 13th 📆 for the Webinar with Dr. Al-George and Dr. Elena Govorunova as invited speakers. Register here: ow.ly/VAhg50OUQpZ

Novel gene therapy may help treat a fatal developmental epilepsy syndrome that affects children Journal of Clinical Investigation doi.org/gsc8r5 medicalxpress.com/news/2023-06-g…

This year's KCNQ2 Cure Family & Professional Summit is just around the corner! Don't miss out & make sure to register. More information can be found on our website: kcnq2cure.org/2023-summit #kv7 #raredisease #ionchanneldisorder #ionchannel #kcnq2 #kcnq2EEE #cure #kcnq2summit2023

Great talk on alcohol induced changes in striatal 2-AG release at #cannabinoidGRC2023 by ⁦Dr. Shana M. Augustin⁩ from ⁦Northwestern Feinberg School of Medicine⁩ ⁦NM Psychiatry⁩

The annual #scn2a FamilieSCN2A conference has started. At (pre-)day 1, academic & industry scientists discuss together with leaders of the foundation board ongoing research & future directions towards better care & medicines.

Latest research reveals impact of SCN2A gene mutation on eye reflexes, shedding light on autism. Altered light response holds clues to sensory challenges in autism. Exciting progress in understanding #AutismResearch #SCN2A #SensoryProcessing spectrumnews.org/news/mutation-…

Thank you to NeuroWoodworks for the beautiful Core Value awards! Congratulations to Praxis Medicines , Al George , Stacey Cohen, and Heather Olson for exemplifying our core values of Urgency, Collaboration, Integrity, and Inclusion. #SCN2A

Happy pi approximation day! Today's date, 22 July, can also be written as the fraction 22/7, which is equal to 3.14285714, an approximation of π, correct to two decimal places.

The 2023 SCN2A Family & Professional Conference is in the books! 320 attendees 100 profs at the Research Roundtable 56 global families 13 #SCN2A posters 7 research opps for families 2 sibling field trips 1 dance party 💃 Too many connections & memories to count… #cureSCN2A

Really interesting new structure of the KCNT1-encoded sodium-activated K+ channel reveals Na+ binding sites on the regulatory RCK domains. Might be an interesting binding pocket for inhibitors. doi.org/10.1016/j.celr… #KCNT1 #epilepsy #ionchannels

Our study of calmodulinopathy in mice demonstrated catecholamine-inducible ventricular arrhythmia that is more severe in males and refractory to flecainide. ahajournals.org/doi/10.1161/CI… #CardioTwitter #Cardiology #calmodulin

Please join the Department of Pharmacology for the Annual Narahashi Lecture with special guest speaker Adrian R. Krainer, PhD. "Antisense Modulation of RNA Splicing for Rare Disease Therapy" 📅Monday, September 11 🕑3:00 pm CST Learn more: bit.ly/3qG7DSQ

Our October cover shows how #epilepsy-associated pathogenic variants in the human voltage-gated sodium #ionchannel NaV1.2 exhibit complex dysfunction. From a study by Thompson et al. (bit.ly/3EV9w1m) Read JGP’s October issue: bit.ly/46as9KO

BREAKING NEWS The 2023 #NobelPrize in Chemistry has been awarded to Walter White for promoting an understanding of synthetic organic chemistry to the general public. This unprecedented selection is bound to spark controversy, but Walter is/was an undeniably inspiring figure...

Perhaps the editor meant ”extracellular field potential recordings”. Action potentials are still technically transmembrane events. Right? It’s still cool.

A new study reveals key mechanisms of rare form of early-onset epilepsy. #ReviewedPreprint elifesciences.org/reviewed-prepr…

Confession - we don't just work on ion channels. Shocking I know. See evidence of this on bioRxiv now. Great to collaborate with @KearneyLab to model alternating hemiplegia of childhood in mice. #ahcawareness biorxiv.org/content/10.110…

Registration is now open for the 2025 Gateway Ion Channel Symposium in Chicago bit.ly/4ioKoRY! Trainees will have opportunities to give short talks and/or posters; please consider submitting an abstract bit.ly/4cE9Xxd.