#ExtracellularMatrix remodeling is a response to chemotherapy, explaining increased tumor spread. This effect is mediated by T-cells expressing LOX. Combined LOX inhibition and chemotherapy can reduce metastasis risk. bit.ly/34YvfXm Daphne Weihs Ruth Shouval

Small subset of highly invasive CD44(+)ALDH(+) #cancer #stemcells can increase metastatic risk. Lower invasiveness CD44(-) cells still pose a risk, possibly resolving conflicting clinical reports. Read here: link.springer.com/article/10.100… Technion Israel ISCR- The Israeli Society for Cancer Research Biomedical Engineering Society European Society of Biomechanics

I was so excited to present the mission and progress of the #Prophylactic #Dressing #Standards #Initiative (PDSI) Task Force at the NPIAP 2022 Conference live today in Tampa FL, USA! I have not done this in-person in such a long time! EPUAP

Our new Acta Biomaterialia paper: How closely adjacent cells can indirectly interact through a gel to increase #Cancer invasiveness! #mechanobiology & #force Technion Israel American Cancer Society ISCR- The Israeli Society for Cancer Research Biomedical Engineering Society European Society of Biomechanics Read here: sciencedirect.com/science/articl…

Our Cell&MolecLifeSci paper shows CD44+ALDH+ breast #cancer #stemcells are highly invasive (#innovative assay) & increase metastatic risk! CD44- cell invasiveness resolved conflicting clinical reports. Read: shorturl.at/vBI47 Technion Israel ISCR- The Israeli Society for Cancer Research Biomedical Engineering Society European Society of Biomechanics

Closely adjacent cells may be more invasive than well-spaced cells due to indirect interactions that increase #Cancer invasiveness and #metastasis risk! #mechanobiology & #force Read Acta Biomaterialia: sciencedirect.com/science/articl… Technion Israel American Cancer Society ISCR- The Israeli Society for Cancer Research Biomedical Engineering Society European Society of Biomechanics

Our new #article reviewing groundbreaking #ArtificialIntelligence #methodologies in #WoundCare - including our own latest contributions to the field - was just published in Advances in Wound Care (Journal of the WoundHealingSociety): liebertpub.com/doi/10.1089/wo… @DimitriBeeckman Skin Integrity Research Group

Ready for European Society of Biomechanics_2022 in beautiful, windy #Porto #ESBiomech2022 @ESBiomech ESBiomech Community

Enjoyed speaking about our #cancer assay to quantify clinical #tumor #invasiveness and #metastasis likelihood using #mechanobiology #ESBiomech2022 European Society of Biomechanics_2022 @ESBiomech Technion Israel ESBiomech Community

We're hiring! Lab manager position at the Technion Israel To apply: bit.ly/3NOBTQO linkedin.com/posts/chen-seg…

What a lovely evening with my friend Dr. Anna-Barbara Schlüer in the #TelAviv port after her visit to my lab at Tel Aviv University today!

Our Gefen Lab INFLUENCE ZONE approach has the capacity to guide #WoundCare #Research & #Development work and clinical decision-making in #negative #pressure #wound #therapy (#NPWT). This is featured in the new BJN issue: magonlinelibrary.com/doi/abs/10.129… Mölnlycke Health Care Mölnlycke U.S.

Wonderful time learning and socializing with colleagues EPUAP 2022 in #Prague #CzechRepublic. A wonderfully run conference! NPIAP Dr. Tod Brindle Amit Gefen Daphne Weihs Martin Burns #pressureinjury @DimitriBeeckman

#hiring #PhDposition at Daphne Weihs lab Technion Israel for #mechnobiology of #cancer and #wounds. Exciting #translational research, experiments, #finiteelementanalysis, #imageprocessing, and #machinelearning. See weihs.net.technion.ac.il Biomedical Engineering Society European Society of Biomechanics ESBiomech Community

Had a lovely evening last night with Amit Gefen and our long-time friend Professor Hans Van Oosterwyck Head of the outstanding MAtrix #Mechanobiology #research Group in the #biomechanics section at KU Leuven!

It was a pleasure to give the plenary guest talk this morning on #PressureUlcer (Lisa Durrant) #etiology and #prevention at the NIFS Norwegian Wound Care Society Conference in #Oslo #Norway, thank you for inviting me! EPUAP

Our new paper, with Qiyao (Alice) Peng and Daphne Weihs, is available at doi.org/10.1016/j.jmbb… The paper deals with a mathematical model for cells that transmigrate through narrow deformable channels. This process is important in the context of metastasis of cancer.

Very happy to see the paper is now fully online! I am looking forward to the next collaboration!

Fred Vermolen is presenting our most recent work at CMBBE regarding cancer cell metastasis, which is a joint work with Daphne Weihs. This work has been published on Journal of Mechanical Behavior of Biomedical Materials. #MathematicalBiology #CMBBE2023