Let the debate begin! Aimee Lucas arguing that patients with BRCA1/2, PALB2, & ATM pathogenic mutations and no family history of pancreatic cancer SHOULD undergo pancreatic cancer surveillance #CGAIGC24

1/Welcome to the January 2025 #CGAIGCJS Tweetorial on “#ColorectalCancer Incidence and Mortality After Negative #Colonoscopy Screening Results” by #CGAIGC Communication committee member Dan Li ➡️Full article in JAMA Oncology at jamanetwork.com/journals/jamao… 🧵 #HereditaryGICancer

IARC convened Working Group to discuss current practices & provide guidance on implementation of popltn-based #Hpylori screen-&-treat strategies for gastric #cancer prevention under EUROHELICAN project. Findings to be published as IARC Working Group Report iarc.who.int/news-events/ia…

📢New ACG Guideline: Gastric Premalignant Conditions Highlights: 🚨GPMC Dx 🚨endoscopic & nonendoscopic management 🚨histology criteria & reporting 🚨H. pylori eradication 🚨autoimmune gastritis 🚨gastric epithelial polyps Read: bit.ly/acg-gpmc-2025

🍄 Kudo pit pattern classification

1/Welcome to #CGAIGCJS Tweetorial on "American Gastroenterological Association (AGA) Clinical Practice Update on Screening & Surveillance in Individuals at Increased Risk for #GastricCancer in the United States: Expert Review” by #CGAIGC Comms Cttee member Monika Laszkowska, MD, MS ➡️Full article in Gastroenterology at

6/ ✅ Findings on the index EGD guide subsequent management Josie Baker Emma Keel (she/her) Ophir Gilad Kristen Ciombor Sharlene Gill, MD, MPH, MBA, FASCO Klaus Mönkemüller, MD, PhD Dr. Despina Siolas, MD, PhD

New ACG Highlights on 🆕 ACG Guidelines for Diagnosis & Management of Gastric Premalignant Conditions (GPMC) ▪️Endoscopy pearls🔦 ▪️Histology pearls 🔬 ▪️Recognizing Correa cascade 🦀 ▪️Non-dysplastic GPMC Mgmt ▪️Dysplastic GPMC Mgmt 📄 gi.org/wp-content/upl…

🧵1/ 🚨 Just out: the PLSD's biggest prospective study yet on Lynch syndrome & colorectal cancer (CRC) surgery. What’s the real risk of a second CRC—and can surgery prevent it? Spoiler: Prior CRC = higher risk. Extended surgery = game changer. 👇 🔗 doi.org/10.1093/bjs/zn…

📈 H. pylori infection significantly elevates fecal calprotectin—often into ranges prompting IBD workup. HP+ kids had higher FC & were more likely to undergo colonoscopy. #pediatrics #pedsgi 🔗 doi.org/10.1002/jpn3.1…

Agreed. In 2025, MSI and MMR IHC should be used to decide who gets immune checkpoint blockade therapy - not to decide who gets germline genetic testing.

1/ Welcome to #CGAIGC Tweetorial on “Diagnostic Utility of FIT in #LynchSyndrome” by CGA-IGC Communications Cttee member Anna Strang, MS, CGC (she/her) ➡️Full article in AJG - The American Journal of Gastroenterology at 👉pmc.ncbi.nlm.nih.gov/articles/PMC11… 🧵 #HereditaryGICancer

I know these faces look familiar! Our past president, Bryson Katona, hosted the 2nd annual #CGAIGC "Pints and Polyps" Happy Hour during #DDW2025, providing a👍opportunity for our members to catch up, strengthen connections, & build community outside our annual meeting. ➡️Join

1/Welcome to #CGAIGCJS Tweetorial on “Neoplasia Detection Through Colonic Surveillance Among Young Individuals With MSH6/PMS2-Associated #LynchSyndrome” by CGA-IGC communications committee member Dan Li Full article in AJG - The American Journal of Gastroenterology at DOI: 10.14309/ajg.0000000000003369

Breaking post-#ASCO25 publication! >1:8 #patients w/ #gastriccancer/#GC have PGVs on #germlinetesting 35% HRR genes #BRCA1, #BRCA2, etc 17% MMR genes #MLH2, #MSH2, etc >91% of positive #patients had clinically actionable PGVs based on management guidelines or active

1/Welcome to #CGAIGCJS Tweetorial on “Cancer and Overgrowth Manifestations of PTEN Hamartoma Tumor Syndrome: Management Recommendations from the International PHTS Consensus Guidelines Working Group” by #CGAIGC Communications Committee member Monika Laszkowska, MD, MS ➡️Full article in

>13% of #patients w/ #GastricCancer had PGVs w/ #germlinetesting These results support consideration of [#universal] #genetictesting in all #patients w/ #GC c/w link.springer.com/article/10.100… Springer Nature Pedro Uson Junior, MD et al. & ascopubs.org/doi/10.1200/JC… Vivek Subbiah, MD Razelle Kurzrock, MD

1/ Welcome to the #CGAIGCJS Tweetorial on: "Germline Genetic Testing in Patients with Advanced Adenomas: A Prospective Study" by CGA-IGC Communications Committee member Anna Strang, MS, CGC (she/her) 📰Full article in Gastroenterology 👉tinyurl.com/yj4urhze 🧵