Added to the reading list!! ATVB: An AHA Journal #Inflammatory Cell–Derived MYDGF Attenuates #Endothelial #LDL Transcytosis to Protect Against #Atherogenesis | #Arteriosclerosis, Thrombosis, and #Vascular Biology ahajournals.org/doi/10.1161/AT…

How much more evidence is needed?

A new exciting paper from deCODE (Stacey, Zink et al. Nat Gen) on the genetics of clonal hematopoiesis (CH) finds "no evidence that CH is associated with cardiovascular disease". While this contradicts many previous influential papers, it also aligns with many, dividing the

Amazing!!

I’m wishing my dear friend Chanele K Polenz the best as she starts her new adventure in Ottawa. Starting as a trainee in our lab, now a master of many talents, and a truly formidable scientist. It’s her turn to help teach the next generation of trainees. Kick ass! #phinished

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New insights into aortic #macrophage reverse transendothelial migration, featuring (of course) functional #lipid signalling by sphingosine-1-phosphate! Amazing work by Chanele K Polenz and team UHN Research #vascularbiology @researchuoft Department of Laboratory Medicine & Pathobiology UofT Vascular Surgery

Thug (PhD) life  Do you remember your worst day of the PhD?

Thank you UHN Research for the shout out. Great teamwork - we’re thrilled to share this paradigm-shifting story with everyone!

Congratulations @ClementCochain and team!!! Fantastic!

Grad students and postdocs need our support. I know the challenges they face firsthand. When I was at the university, I helped them secure funding, food, housing and heating. They have the ideas, do research now, and are also the future of research. Time to invest.

A fantastic Review article Nature Cardiovascular Research on Immunometabolism in atherosclerotic disorders by Prof Andrew Murphy Dr Andrew Fleetwood Jonathan Noonan 🏴󠁧󠁢󠁳󠁣󠁴󠁿🇪🇺🦦 from Baker Institute and 💮Nicole La Gruta Monash Biomedicine Discovery Institute and KalliesLab Doherty Institute rdcu.be/dITN3 #atherosclerosis

Congratulations Curtis McCloskey!!! Amazing! Superstar on the rise!

This has been a very busy week for Lp(a) papers. This study suggests Lp(a) is associated with high-risk plaques. I put into perspective what technique is best suited to image Lp(a)/OxPL pathophysiology.

First official pub from my time in the Kathryn Howe lab! Congratulations to the team and all who contributed! Stay tuned to see what else the Howe lab cooks up next!! #endothelial #vascular #aging #extracellularvescicles #senescence UHN Research Toronto General Hospital Research Institute Department of Laboratory Medicine & Pathobiology IMS Toronto

Congratulations to Dr. Clinton Robbins and the team at UHN’s Peter Munk Cardiac Centre on their new study published in Nature Immunology. Their work reveals how cigarette smoke can trigger deadly aortic aneurysms—and points the way to life-saving treatments. Read more: nature.com/articles/s4159…

Mandy Kunze Guo et al found that endothelial cell communication can be tracked in #atherosclerosis. Endothelial-derived #EVs can be detected within #macrophages deep within plaques ahajrnls.org/43H7vSc Kathryn Howe Jason Fish Corey A Scipione Sneha Raju Steven Botts Sarvatit Patel

This #StrokeAwarenessMonth, a team led by Dr. Kathryn Howe from University Health Network’s Toronto General Hospital Research Institute reveals how blood vessels cells send tiny messages that may trigger plaque rupture and stroke, generating a first-of-its-kind model to help investigate further. 🔗 Read more: uhnresearch.ca/news/how-arter…