I'm excited to share that I will be starting my lab at NTU Singapore. It is bittersweet to be moving halfway around the world. On one hand, I'm excited for a new adventure. I have spent my entire adult life chasing this dream, and it's finally happening. On the other hand, I

We have the chance to rid the world of cervical cancer - effectively eliminate it How? A vaccine! The HPV vaccine prevents cancer!

Rich Condit travels to Dubrovnik for European Congress of Virology 2025 & Vincent joins via Zoom to speak with Stéphane Blanc, Vanda Juranić Lisnić, & Elisabeth Puchhammer-Stöckl about their work on plant viruses, cytomegalovirus, & Epstein-Barr virus. 📺 bit.ly/3SZ7apg

News: The American Academy of Pediatrics says it will no longer take part in the process of ACIP meetings. “We won’t lend our name or our expertise to a system that is being politicized at the expense of children’s health,” the group's president says. statnews.com/2025/06/25/cdc…

Ahh, visiting other labs. Back in my youth, we would just go places and do things. Nobody asked questions, MTAs and TTOs did not exist, and science proceeded 10x more rapidly. Today everybody frets about IP rights which will never generate any $$$, and everything stands still.

TFAP2A+ embryonic progenitor cells undergo fate diversification to give rise to human amnion, germline, and mesoderm biorxiv.org/content/10.110…

My NIDA grant renewal is almost 2 months late and I’m going to have to start firing my students and staff. Not a lot of transformation to be had in my lab.

Ted Koppel interviews my Hopkins colleague Prof. Liz Jaffee, world expert in pancreatic cancer, about the devastating cuts and slow roll out of cancer research funding by the NIH. See this CBS Sunday morning show video here: youtube.com/watch?v=CLwcYQ…

We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease. With such a large scope you need excellent partners, so we are happy to have teamed up with ZZ Zhao Zhang & Vincent Yang Xu nature.com/articles/s4158…

Online now: Generation of germinal-vesicle oocytes from mouse embryonic stem cells under an ovarian soma-free condition dlvr.it/TLf6wf

My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15

We turn 25 today! July 7th marks the 25th anniversary of the human genome going online and the start of the UCSC Genome Browser. Then vs. now, we have 165k monthly visitors, and our codebase is over three million lines of code. See our news for more: bit.ly/genomeBrowser2…

Our next episode features Dr. James Briscoe (James Briscoe) from The Francis Crick Institute! Check out his team's nature paper developing a 3D model of human trunk formation: go.nature.com/4lzKF77

Trying to trace back the steps that led you to agree reviewing the paper

As a graduate student, his research doesn’t show much promise. It isn’t especially innovative, methodologically rigorous, or theoretically compelling. His willingness to throw his co-authors & professors under bus when he underachieves though shows real administrative potential!

The complexity of living systems cannot be fully recapitulated by in vitro or computational approaches alone. While advances in non-animal model technologies offer complementary tools, they lack the full physiological and developmental context of a living organism. 💯

My lab is recruiting post-docs! We study inter-organ communication using cutting-edge tools like proximity labeling (TurboID), in silico modeling (AlphaFold), and genome engineering (CRISPR). Come join us at U of Utah Human Genetics, Utah is beautiful! (View from our fly room 👇)

Animal researchers: please comment on NIH-FDA workshop on reducing animal testing (due by 5pm est today): tinyurl.com/2s492j5n

Your non-renewal has nothing to do with your criticism of the governor, it is purely a financial decision. Speaking of which, I need to see how the remodel of my office is going!

Why do some genetic mutations devastate specific tissues while sparing others? We explore this question in GGC repeat disorders, revealing a mechanism linking protein aggregation to tRNA splicing failure in the brain. 🧵 on our new paper in Science: 🔗 science.org/doi/10.1126/sc…