If science has refuted the assumptions that underwrite your management strategy, and the tests you use have been discredited; why do you believe that change is unnecessary before an RCT proves the point? In fact, is your management justified by RCT? Certainly not for CUTIC.

The evidence associating IC with missed urinary infection is piling up. No surprise; the first test of the diagnostic screening chain is a dud. Dogmatic denial is pointless; so too grasping for rebuttal straws. Far too many suffer the consequences; we must admit and repair.

We are excited to share our first #BIIG publication! A sincere thanks to the editors Mucosal Immunology for inviting us to write a review on #chronicUTI, and the reviewers for their valuable inputs. Available as pre-proof now: sciencedirect.com/science/articl…

Let's revisit a 2018 publication fr James Malone-Lee, Raj Khasriya & team in IUJ International Urogynecological Association (IUGA). It's a first-time ever patient-described 39-point lower urinary tract symptom (LUTS) questionnaire - still useful in diagnosing, treating & monitoring disease progression in #chronicUTI.

Mobility across ecological contexts & continents is more important to describe the worldwide spread of bacterial resistance to aminoglycosides, than the consumption of aminoglycosides itself. -author impact statement.

“Short answer: Probably not, as far as I’ve been able to determine.” “Please err on the side of assuming pain is never psychosomatic”

Can any UTI researchers please help patients understand the 4 tests being considered by the NHS to diagnose UTI and how causation is addressed? - Astrego PA-100 analyser - Lodestar DX (Llusern Scientific) - Uriscreen (Savyon Diagnostics) - UTRiPLEX (Global Access Diagnostics)

Thank you to BSAC for giving me the opportunity to tell my story & amplify the voices of patients suffering with Chronic UTI. We want our lives back & coverage like this is key in our fight for better care & treatment! bsac.org.uk/patient-spotli…

Thanks for having me! - Harry Link to interview: youtu.be/pq1K1zBt7Ho #BIIG #UTI #chronicUTI #Microscopy #CellScience

#BIIG Harry & Raj co-authored this review on why the simplistic/dichotomous interpretation of standard urine culture results is not sufficient/accurate for #UTI diagnosis in modern science. Link: frontiersin.org/articles/10.33… Raj Khasriya Linda Brubaker, Toby Chai MD R Moreland & A Wolfe

And here is how these embedded bladder bacteria look (stained in green) in case you want to see for yourself!

We thank the kind donor for her generous gift. It'll no doubt help nurture a generation of outstanding future scientists & advance #UTI research towards the goal that diagnosis of #chronicUTI becomes a thing of the past! #PhDFellowship #FeelingGrateful 🤗 UCL Renal

THINK LIKE AN EPIDEMIOLOGIST: Science is not magic. It always requires assumptions. When done perfectly, some types of studies make fewer assumptions. But no one’s perfect. We can’t decide quality from study type alone: a good observational study can be better than a bad RCT.

There's so much to address in this article. We are totally on board with encouraging clinicians not to treat asymptomatic bacteriuria. But ignoring cultures with mixed growth and potential 'contaminants' is selective ignorance. healio.com/news/infectiou…

Friend or Foe? #UTI #ChronicUTI #AmazingMicroscopy #SciencePhotography #BiofilmCreate #BiofilmAware National Biofilms Innovation Centre (NBIC)

Unity is Strength (This one's from a healthy person) #UTI #ChronicUTI #AmazingMicroscopy #SciencePhotography #BiofilmCreate #BiofilmAware National Biofilms Innovation Centre (NBIC)

P.Happi Live UTI Free CUTIC Chronic UTI Global Support Dear P Happi. Please let us know if you have been able to answer the following questions about your product: 1. What dose/how many bacteria is in each spray? 2. How do you know the bacteria are alive when they reach the vulva?

Thanks Raj for asking these important questions in the interest of the community. We hope to learn more about the evidence behind such products.