Below was the most striking report in biomedicine over the last week
Now the first trials have begun for multiple sclerosis
nature.com/articles/d4158… nature

Follow the data.

🚩MR Grading with TEER

In our echo/Cath collaborative 📑, we🔬the impact of abn PV flow (systolic blunting/reversal) post-TEER

💢PV flow remains abn in most pts EVEN when final MR is mild
💢Abn PV ⬆️ invasive LAP
💢Abn PV ⬆️ death regardless of MR grade doi.org/10.1016/j.echo…

What is a Valve Center of Excellence?

In our EC “Universal Mastery in Valve Disease Treatment: Myth or Attainable Goal”, we discuss an important study from the TVT registry which showed site-level discordance in the outcomes of TAVR and those of MVTEER jacc.org/doi/10.1016/j.…

Highly provocative and intriguing! Combining a series of independent observations into a coherent hypothesis. Congratulations Rajiv et al.

An excellent way to cross retrogradely is to telescope an angled glide catheter through 6F and cross it using a straight wire. Learned from ⁦Trevor Simard⁩. ⁦Benjamin Hibbert⁩

Pay or Die public premiere is tomorrow. Proud to have played a small part in this important film that highlights insulin and prescription drug costs. #MedTwitter Pay Or Die Film Human Rights Watch Film Festival

A fantastic and very innovative case!

Delighted and honored to present the Orion 8 trial result today at #ESC2023 Hotline session. Long-term use of Inclisiran in patients with ASCVD, ASCVD Risk Equivalents or HeFH achieved pre-specified LDL-C goals (LDL < 70 in ASCVD, < 100 in others) nearly 80% at 3 year f/u.

Truth

⁦Mayra Guerrero, MD⁩ presenting amazing results from the intermediate risk MVIV analysis at TVT today.

Standardising TAVI procedures: a step towards improved patient care

Cusp overlap technique versus 3-cusp coplanar view: advantages and implications of a precise, tailored valve implantation depth of self-expanding Evolut platform
Good article!
eurointervention.pcronline.com/article/standa…

Among pts undergoing #TEER , optimal hemodynamic response is achieved in 42%.

AF, higher baseline LAP & higher postprocedural mitral gradient were negative predictors.

🔗doi.org/10.1002/ccd.30…

✍️Mohamad Alkhouli Mayra Guerrero, MD Chet Rihal et al

Thanks for a great summary Matt.

Hard to overstate the importance and influence of training under David Holmes had on the career of a young interventional cardiologist. What a night!

Pulmonary artery pulsatility index in patients with tricuspid regurgitation: non-invasive, easy and meaningful. Check it out at European Heart Journal - Cardiovascular Imaging | Oxford Academic academic.oup.com/ehjcimaging/ad…

Very important study.

Revisiting 🧬 testing for post PCI APT Tx?

In this prespecified analysis of TAILOR PCI, cumulative incidence of ischemic events at 12 months were ~40% lower with genetics guided approach via conventional Tx. jacc.org/doi/10.1016/j.…