Workshops focused on gene editing tools applications 🧬 and safety merhods to control genotoxicity 🔎at #crisprmed25 from Cost Action GenE-Humdi Ceron Lab and Carla Fuster

Llevo unas semanas con más estrés del habitual que impide disfrutar de cosas de mi trabajo y de otras fuera de él, como los raticos de ciencia. Pero ha pasado un mes sin sacar podcast y aún así se siguen escuchando episodios, solo en ivoox unos 100 x dia. Gracias! Vuelvo pronto😘

#CRISPR-Cas toolbox growing 👇

Transplanting dopamine-releasing neurons into the brain is a promising regenerative therapy for Parkinson’s disease go.nature.com/3YqeI7J

Prime editing in hematopoietic cells is improved by engineering nucleotide metabolism go.nature.com/3X2vUjx rdcu.be/eh3ak

La mitigación del cambio climático depende, sobre todo, de los grandes emisores y los sistemas de producción, pero es posible avanzar mucho en la adaptación con acciones individuales, locales y nacionales. Aquí lo contamos: #EthicMagazine ethic.es/como-sobrevivi…

Cas9 gets an upgrade! Check out our new paper in The CRISPR Journal: bit.ly/hiNLS-Cas9 Eric Noel (who is on the job market!) created Cas9 constructs w/ nuclear localization signals (NLS) in the backbone, boosting genome editing activity in T cells. #CRISPR

In @nature we describe the use of scalable #proteinengineering & #machinelearning to predict millions of bespoke CRISPR-Cas9 enzymes, offering safer & more genome editing tools. 🧬🖥️ Rachel Silverstein CGM at MGH @MGH_RI MassGeneral News Harvard Medical School nature.com/articles/s4158…

Prime editing efficiency is enhanced using a mutated reverse transcriptase and addition of deoxynucleosides go.nature.com/4gB6917 rdcu.be/eh3bF

By combining high-throughput protein engineering with machine learning, bespoke SpCas9 enzymes are identified that outperform evolution-based and engineered nucleases and base editors in human cells. nature.com/articles/s4158… #NBTHighlight

I've been waiting for the day I could make this video! Retrotransposons are reprogrammed for pretty efficient gene insertion up to 12.7kb in user-defined genomic targets. Small deletion + insertion possible too. Awesome work from Jonathan Gootenberg Omar Abudayyeh Chris Fell

Last minute submission for an oral talk at the @SEGenetica meeting. See you in july in Cartagena (Murcia)😍

👏👏Excelente entrevista Manuel!! 🏆Para mi, uno de los mejores programas de ciencia en castellano. 🎙#RaticosdeCiencia tiene una cita con Óscar Marín el próximo 5 de mayo en Barcelona. A ver si reactivo el podcast que no me daba la vida.

Fijaos en cómo Cubarsi le dice a Pedri que corra al espacio.

🚨 2025 Modena Summer School is considering Applications. 🧬 Hone your #GeneEditing Skills 🫂 Met @genehumdi experts 🚀 and push your career forward by attending our Summer School from June 18 to June 20 in Modena. Full program and application Forms: genehumdi.eu/2025-modena-su…

A tissue-specific atlas of protein–protein associations enables prioritization of candidate disease genes go.nature.com/3Z1q0PM

¿Quieres trabajar en el IBV-CSIC y hace menos de 3 años que acabaste la carrera? ¡Tienes de tiempo hasta el viernes 9 de mayo! sede.csic.gob.es/tramites/convo…

Scientists in Feng Zhang's lab have re-engineered a compact RNA-guided enzyme they found in bacteria into an efficient, programmable editor of human DNA. Nature Biotechnology Feng Zhang Broad Institute MIT Brain and Cognitive Sciences MIT Science mcgovern.mit.edu/2025/05/08/rat…