Cell Regen Review | Rewiring cardiomyocyte identity & metabolism for heart regeneration!🫀Strategies for improving cardiac function in animal models. #HeartRegeneration #StemCells 🔗 More at: doi.org/10.1186/s13619…

Cell Regen Report | Validating quality standards for primary human hepatocytes! Tested viability, markers & metabolism in hepatocytes, revealing heterogeneity for liver studies. #Hepatocytes #CellBiology 🔗 More at: doi.org/10.1186/s13619…

Cell Regen Research | Posterior enhancer (p-Enh) maintains neuromesodermal progenitor bi-potency during gastrulation! Deletion biases fate toward presomitic mesoderm, thereby disrupting spinal cord development. #StemCells #Embryogenesis 🔗 More at: doi.org/10.1186/s13619…

Cell Regen Review | 📝Hypoxic–ischemic preconditioning (H/IPC) protects the 🧠 via mitochondrial metabolism—H/IPC boosts mitophagy, curbs fission & apoptosis for neuroprotection. #Mitochondria #Neuroprotection 🔗 More at: doi.org/10.1186/s13619…

Cell Regen Review | Poly(A) tails: the hidden switch in stem cell fate & early development! Length dynamics drive mRNA stability & translation. #StemCells #RNAbiology 🔗 Full review at: doi.org/10.1186/s13619…

Cell Regen Research | 🔎Single-cell atlas reveals lifelong evolution of bone marrow vascular niche! From fetal liver to aged BM, Midkine emerges as a new regulator of HSPC reconstitution. #Hematopoiesis #StemCellNiche 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Report | Major step forward in 🦷! New N2B27-based culture medium keeps mouse dental mesenchymal cells odontogenic for 14 days — BMP4 down, OPN/ATRA — enabling regenerative teeth in vivo. #ToothRegeneration 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Research | 🎯Direct Oct4 targets in ESCs revealed! Auxin-inducible degron (AID) system + nascent RNA-seq uncovers immediate transcriptional changes in pluripotency genes & non-coding RNAs. #StemCells #Pluripotency 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Review | Imaging + single-cell omics: a new paradigm in developmental biology! 🔬Super-resolution & light-sheet meet spatial transcriptomics for multi-scale insights. #DevelopmentalBiology #SingleCellOmics 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Research | α-Ketoglutarate boosts skin flap survival! 🩹 Enhances angiogenesis via PI3K/Akt/HIF-1α in ischemic flaps. #Angiogenesis #WoundHealing 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Report | Mammalian MSCs enhance zebrafish fin regeneration! 🐟MSC-derived PGE2 regulates macrophage recruitment & resolution, boosting repair. #Regeneration #Macrophages #StemCells 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Research | CPP drives rapid endothelial differentiation of umbilical cord MSCs! 🧬🧬🧬>90% VEC conversion in 5 days via MEG3 regulation—functional in vitro & in vivo. #StemCells #VascularRegeneration 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Research |✨Primed hPSCs → functional trophoblast stem cells in days?🧬 Transient MEK/ERK inhibition + balanced WNT yields stable hTSCs with strong STB/EVT potential. #StemCells #Trophoblast 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Research | LncRNA-IH drives cardiac fibrosis after myocardial infarction!🫀 Overexpression worsens remodeling & activates TGF-β1/ZEB1 in fibroblasts. #CardiacFibrosis #HeartFailure 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Research | A new mouse model for precise endothelial cell ablation! 🩸Dual Cre/Dre logic activates DTR for precise vascular studies. #EndothelialCells #GeneEditing 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Research | Neonatal muscle extracellular vesicles speed up muscle repair! 🩹 Activate satellite cells, boost regeneration, and reduce fibrosis/fat infiltration in glycerol injury models. #MuscleRegeneration #StemCells 🔗doi.org/10.1186/s13619…

Cell Regen Research | Even spaceflight-like aging reveals MRG15 as a key player🧩 in muscle stem cell regeneration! Its decline in aged/injured MuSCs impairs regeneration via MyoD disruption & histone changes. #MuscleRegeneration #StemCells 🔗Full article: doi.org/10.1186/s13619…

Cell Regen Research | Frizzled-related protein (FRZB) protects periodontal ligament stem cells from inflammation-induced osteogenic defects!🦷Inflammation downregulates FRZB and impairs osteogenesis; FRZB overexpression restores.#Periodontitis #StemCells 🔗doi.org/10.1186/s13619…

Cell Regen Research | Embryonic intestinal Lgr5⁺ cells prior to villification (PVLCs) actively shape small intestinal morphogenesis before villi form via Hedgehog signaling! #Cellfate #IntestinalDevelopment 🔗 Full paper at: doi.org/10.1186/s13619…

Cell Regen Research | Lysine crotonylation delays adipose-derived mesenchymal stem cell senescence & boosts efficacy in IBD! NaCr restores Kcr, suppresses NF-κB, and enhances anti-inflammatory effects. #StemCells #InflammatoryBowelDisease 🔗Full paper at: doi.org/10.1186/s13619…