cryostat2 (@cryostat_2) 's Twitter Profile
cryostat2

@cryostat_2

ID: 875600339071770624

calendar_today16-06-2017 06:26:03

814 Tweet

1,1K Followers

507 Following

Karim Brohi (@karimbrohi) 's Twitter Profile Photo

Seismic next three days for trauma research with the results of 3 big RCTs at criticalcarereviews.com Belfast. Free livestreams: Tomorrow 8am UTC: UK-REBOA UKREBOATrial ; 11am: PATCH (@PatchTrial) & most importantly (!) Friday 8am: CRYOSTAT-2 cryostat2

Magpas Air Ambulance (@magpas_charity) 's Twitter Profile Photo

The summer weather has hit us here in the East of England. However, despite the heat, our doctors and paramedics are still donning their protective uniforms and heavy boots, and travelling across the region to provide patients with lifesaving care when every second counts.

The summer weather has hit us here in the East of England. However, despite the heat, our doctors and paramedics are still donning their protective uniforms and heavy boots, and travelling across the region to provide patients with lifesaving care when every second counts.
Critical Care Reviews (@critcarereviews) 's Twitter Profile Photo

#CRYOSTAT2trial #CCR23 cryostat2 primary outcome by timing of cryo non-sig difference in mortality per timing of delivery defining the optimum time point - worse outcomes if given early, and worse later...

Tim Coats (@tjcoats) 's Twitter Profile Photo

Interesting discussion from cryostat2 results presentation. Trial primary result = no difference. Major trauma with bleeding is not one disease so looking for one treatment protocol may be an incorrect approach. We would not research to find a treatment that works for โ€˜cancerโ€™.

Karim Brohi (@karimbrohi) 's Twitter Profile Photo

CRYOSTAT2 results #ccr23: - Early *empiric* administration of high-dose cryoprecipitate to trauma patients activating the major haemorrhage protocol did not improve 28-day mortality. - possible evidence of harm if given very early or in penetrating trauma patients...

Karim Brohi (@karimbrohi) 's Twitter Profile Photo

In the meantime some cryostat2 data from our #ccr23 presentation. Wait for the paper ofc, but I'd suggest: - If you're thinking about giving concentrated fibrinogen (in any form) up front to trauma patients, don't. - Prioritise getting fibrinogen (FIBTEM/FF) levels back asap

In the meantime some <a href="/CRYOSTAT_2/">cryostat2</a> data from our #ccr23 presentation. Wait for the paper ofc, but I'd suggest:

- If you're thinking about giving concentrated fibrinogen (in any form) up front to trauma patients, don't.

- Prioritise getting fibrinogen (FIBTEM/FF) levels back asap
Andrew Petrosoniak (@petrosoniak) 's Twitter Profile Photo

Karim Brohi cryostat2 ๐Ÿ™๐Ÿ™๐Ÿ™ amazing work. Look forward to reading the paper. Helpful to know that cryostat2 doesnโ€™t disrupt motion that once hypoF IS identified that replacement is still beneficial! But love your point about not doing anything empirically to trauma pts! ๐Ÿคฃ seems to be true!

Karim Brohi (@karimbrohi) 's Twitter Profile Photo

I did warn you this week would be seismic for trauma research & resuscitation! Papers need to be published & digested. Dust needs to settle. Things have changed. Huge thanks to Rob, Emma & the whole Critical Care Reviews team for an incredible meeting & for selecting CRYOSTAT2 ๐Ÿ™๐Ÿผ.

I did warn you this week would be seismic for trauma research &amp; resuscitation! Papers need to be published &amp; digested. Dust needs to settle. Things have changed.

Huge thanks to Rob, Emma &amp; the whole <a href="/CritCareReviews/">Critical Care Reviews</a> team for an incredible meeting &amp; for selecting CRYOSTAT2 ๐Ÿ™๐Ÿผ.
Karim Brohi (@karimbrohi) 's Twitter Profile Photo

A massive day for UK trauma with the publication in JAMA of two game-changing trauma trials: cryostat2 and UKREBOATrial. Both turning points in how we understand and treat trauma patients. UK-REBOA: jamanetwork.com/journals/jama/โ€ฆ CRYOSTAT-2: jamanetwork.com/journals/jama/โ€ฆ

Karim Brohi (@karimbrohi) 's Twitter Profile Photo

With so much horror everywhere in the world, we must keep improving trauma care through research and global education. For us at CommsC4TS it's our path to try to make a difference, to try to make these events a fraction less terrible. Until humans stop hurting other humans.

Professor Beverley Hunt OBE (@bhwords) 's Twitter Profile Photo

Congratulations to all involved in this study, itโ€™s a great achievement for all involved, including Nikki Curry Simon Stanworth, Ross, a truly excellent clinical trials team and of course Karim Brohi Iโ€™m proud to have chaired the steering committee for you.

Marion Campbell (@marionkcampbell) 's Twitter Profile Photo

Our UK-REBOA trial is out. A huge endeavour with major implications for UK trauma care-showing that use of #REBOA in the ED for exsanguinating haemorrhage did not reduce, and may increase mortality. Huge thanks to the entire trial team. Jan Jansen jamanetwork.com/journals/jama/โ€ฆ

Karim Brohi (@karimbrohi) 's Twitter Profile Photo

Wonderful (and very generous) write up/run down of cryostat2 and its implications by the Saint Emlyn's team. stemlynsblog.org/cryostat-2-st-โ€ฆ ๐Ÿ™๐Ÿผ

Karim Brohi (@karimbrohi) 's Twitter Profile Photo

Update for next week's national major trauma haemorrhage meeting: eventbrite.co.uk/e/uk-major-traโ€ฆ Over 600 people signed up online or in person over the 2 days. We are FULL in person for Day 1, but you can still add to a waitlist if anyone drops out. Still places in person for D2 and