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A The PurdonLab classic.

Thanks to all who joined us at our Year-End Symposium and Research Showcase to learn about promising studies on brain resilience supported by the Knight Initiative. Congrats to our 2025 poster session winners: Vanessa Doulames, Lauren Duan, Shuke Xiao, and Shon Alimukhamedov!

Congratulations to Shuke on your poster prize!

Really excited to receive a poster award and this very thoughtful gift! Thank you!

A newly discovered biomarker in spinal fluid—the YWHAG:NPTX2 ratio—may indicate who will develop dementia and how quickly it will progress, according to a Nature Medicine study led by Hamilton Oh and senior author Tony Wyss-Coray. brainresilience.stanford.edu/news/new-prote…

What does resilient brain aging look like? Stanford researchers Beth Mormino Mormino Lab and Anthony Wagner share insights from the Stanford Aging and Memory Study, revealing how some people maintain cognitive health well into their 80s and 90s. 🔗 neuroscience.stanford.edu/news/secrets-r…

For neurodegenerative diseases like Alzheimer’s and Parkinson’s, treatment options are scant. New research identifies a promising access point to therapeutics. news.stanford.edu/stories/2025/0…

Mislocalization of proteins is common in cancer and neurodegenerative disease. Institute Scholar Steven Banik developed a technology to relocate errant proteins, with the hope of correcting cellular problems caused by protein misplacement: go.nature.com/3H3Su5w

Congratulations to our 2025 Catalyst Momentum awardees! Their projects explore how sleep, inflammation, endocannabinoid metabolism, cellular stress, microglia, and other factors shape brain aging and resilience. Learn more: brainresilience.stanford.edu/news/fueling-n…

What if a brain implant could treat neurological disorders and restore communication for those who have lost the ability to speak? Stanford Neurosurgeon Jaimie Henderson discusses advancements in BCIs and clinical trials for TBIs in our latest episode. neuroscience.stanford.edu/news/best-how-…

🧠 Small businesses are an essential part of the innovation ecosystem for aging research. This #AlzheimersAwarenessMonth, see how our #SBIR & #STTR programs are supporting their contributions to the fight against #AlzheimersDisease: go.nih.gov/e6epOI5

"With all the advances in both the science of aging and [#AI], we are in a propitious position to accurately and precisely determine who is at high risk of developing #AlzheimersDisease years before signs of even mild cognitive deficit," writes Eric Topol in a new

Everyone has been impacted by Alzheimer’s or knows someone who has. In honor of Alzheimer’s & Brain Awareness Month, #GoPurple and learn how you can take action to #ENDALZ: alz.org/abam.

At a recent seminar, Hannah Ennerfelt shared a talk on "Peripheral immune drivers of cognitive decline in aging & AD," and Jintao Sheng discussed "Top-down attention & Alzheimer’s pathology impact cortical selectivity during learning, influencing episodic memory in older adults."

💡IMO one of the best use of AI Scientist is to reanalyze data to find new insights. Introducing #CellVoyager: AI Compbio Agent that makes new discoveries by autonomously analyzing papers/data, which we then validate🚀 New findings on aging, Covid, scRNAseq etc. Open source!

High throughput data are goldmines that we often only scratch the surface. Great for AI to systematically analyze! CellVoyager makes Jupyter notebooks 📜biorxiv.org/content/10.110… 💻github.com/zou-group/Cell… Great job Samuel Alber Bowen Chen Eric Sun Aaron Wilk Alina Isakova