Now out on bioRxiv! Thank you to our alum Becca J. Carlson for this great Tweetorial! Broad Institute

New bioRxiv! w/ our high-throughput screening approach, screened 1.3M+ antibiotic combos against high priority, drug-resistant bacterial pathogens, identified small molecule P2-56 as a potentiator of rifampin against A. baumannii and K. pneumoniae biorxiv.org/content/10.110…

We are excited to share our new bioRxiv about CROPseq-multi with the community, many thanks to our Russell Walton for this Tweetorial about his work with Yue Qin! Broad Institute MIT Dept of BE Eric and Wendy Schmidt Center

Excited to share our preprint on metabolic differences in the vaginal #microbiome . We find key differences in fatty acid metabolism among #Lactobacillus species & leverage those findings to identify a potential new therapy for bacterial vaginosis (BV) & #WomensHealth 🧵 (1/n)

And check out the fantastic MIT News piece by Anne Trafton about our STING paper news.mit.edu/2023/study-fin…

Irvine Lab and Blainey Lab discovered that STING protein has previously unknown role as an ion channel, helping cells respond to danger signals such as viral infection.ow.ly/PuV150Psqgu Blainey Lab Science Magazine Koch Institute at MIT Broad Institute Ragon Institute

Our latest study, in collaboration with the Hacohen and Irvine labs, is out now in Science Magazine! It's a great story about a surprising finding regarding the mechanism of a human immune sensor science.org/doi/10.1126/sc…

We are pumped to share with the community our new Nature Biotechnology paper on high-throughput RNA isoform sequencing with MAS-ISO-seq from a great collaboration across Broad Institute nature.com/articles/s4158…

Out now in Science Advances, our collaboration with the Hacohen lab on #StimDrop - antibody-based cell barcoding with parallel droplet processing to explore cellular responses in a large combinatorial space science.org/doi/10.1126/sc… Broad Institute

ICYMI, the inaugural Broad Institute Discovery Series talk featuring Paul Blainey and Alex Shalek is available for on-demand viewing! youtube.com/watch?v=_bLPh4…

New #ResearchHighlight in Nature Reviews Genetics about our recent Cell paper with Iain Cheeseman lab! Broad Institute Whitehead Institute

CRISPR screening + cell imaging 👏 Congrats Iain Cheeseman and Blainey Lab teams! Everyone should check out this paper showcasing how precise functional insights can be extracted from fluorescence microscopy. cell.com/cell/fulltext/…

The holidays are coming up and if you need something to read during your time off, we've got you covered: out now in Mol Syst Biol is our review by Russell Walton Avtar Singh and Paul Blainey on optical pooled screening approaches! Broad Institute embopress.org/doi/full/10.15…

'The resource we’ve created will benefit not just our own lab but labs around the world,' @Iaincheeseman says.

Using a novel image-based screening method, researchers in the Cheeseman lab evaluated the functions of over 5,000 essential human genes: wi.mit.edu/news/scientist…

Online today in Cell! Our fab collaboration with Iain Cheeseman lab: image-based screen 5K+ essential genes to build a resource defining the phenotypic consequences of disrupting core cellular processes Broad Institute Whitehead Institute Luke Funk cell.com/cell/fulltext/…

We are thrilled to be a part of Phase 2 of the Chan Zuckerberg Initiative #NDChallengeNetwork with the Lagier-Tourenne and Jain labs! CZI Science Broad Institute

Join us in person or virtually for our upcoming CV research symposium Broad Institute on October 18th from 9a-1p EST.

Part of our collaboration with Bayer | Pharmaceuticals, but open to all in academia, pharma & biotech.