Nature research paper: De novo design of protein structure and function with RFdiffusion nature.com/articles/s4158…

Happy to share our work on a new multicomponent process merging the isonitrile-tetrazine (4+1) cycloaddition and the Ugi-4 component reaction. Congratulations to all authors @gbernardes_chem, Aldrin Vasco, Tiago Rodrigues, Jimenez-Oses Lab

Happy to be on board!

🚀 ¡Estrenamos #podcast! No te puedes perder el primer #episodio en el que, junto a Jimenez-Oses Lab, exploraremos cómo la #IA está #transformando la #ciencia. ¡Prepárate para adentrarte en el #futuro de la ciencia! 🎙️ ow.ly/u5bl50PLuiC #BioEnredados #UniendoCienciayVida

🎉 Excited to share that our paper "De novo design of high-affinity binders of bioactive helical peptides" is officially out! nature.com/articles/s4158… Hats off to coauthors Phil Leung and Preetham Venkatesh for making this project a reality. 🙌 Grateful for their collaboration!

Thrilled to share our latest joint work with the Baker lab Institute for Protein Design on improving protein expression, stability and (catalytic) function just published in J. Am. Chem. Soc.. Congrats Kiera and Reyes! CIC bioGUNE BRTA - Basque Research and Technology Alliance Ikerbasque pubs.acs.org/doi/10.1021/ja…

📈 Read one of our recent most read #OpenAccess articles, "Improving Protein Expression, Stability, and Function with ProteinMPNN" Jimenez-Oses Lab Institute for Protein Design CIC bioGUNE BRTA - Basque Research and Technology Alliance Ikerbasque Read the article here ➡️ go.acs.org/7Kk

Our review "Machine learning approaches in predicting allosteric sites" with F Nerin ALLODD is now open access at Current Opinion/Research in Structural Biology Elsevier Biomedchem sciencedirect.com/science/articl…. The full issue on "Sequences & Topology" and #allostery is now open! Read it here: sciencedirect.com/journal/curren…

Happy to share our latest contribution to the Kemp eliminase field. Good friends and good memories! CIC bioGUNE Ikerbasque BRTA - Basque Research and Technology Alliance …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cc…

Announcing AlphaFold 3: our state-of-the-art AI model for predicting the structure and interactions of all life’s molecules. 🧬 Here’s how we built it with Isomorphic Labs and what it means for biology. 🧵 dpmd.ai/3URDiNo

How could #AlphaFold 3 transform drug discovery? Most drugs are small molecules known as ligands that bind to proteins to change how they interact in human health and disease. AlphaFold 3 can predict these interactions to atomic accuracy.

#bioGUNE_Alumni | 🎓 Congratulations, Reyes Núñez Franco, from "Computational Chemistry Lab" Jimenez-Oses Lab for successfully defending her #PhDthesis today! 🎉

Interplay Between Substrate Polarity and Protein Dynamics in Evolved Kemp Eliminases (Gonzalo Jimenez-Oses and co-workers) Jimenez-Oses Lab CIC bioGUNE #openaccess onlinelibrary.wiley.com/doi/10.1002/cc…

WE ARE HIRING!! 4-year Postdoc Research Associate [51.807 € / year] PROJECT: Machine Learning for the Acceleration and Optimization of Pharmacophores for the Design of New Medicines by STD NMR Spectroscopy CONTACT FOR INFORMATION before 7th August

📢Job offer. Momentum: Doctoral Contract at IIQ-CSIC Sevilla CIC bioGUNE Bilbao (Profs. Jesús Angulo and Gonzalo Jiménez-Osés). Project: Machine Learning for the Acceleration and Optimization of Pharmacophores for the Design of New Medicines by STD NMR Spectroscopy (MMT24-IIQ-01)