🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Fantastic paper that exemplifies the credo and mission of Institute of Human Biology: bold and creative young scientists as hands-on leads + projects combining biology, engineering, computation and drug development + extremely close collaboration between multiple research groups! Congrats!!

Super happy to share that our paper is published in nature today! We've discovered how the breast is protected against tumor initiation—though it comes at a cost. 📰Read all about it here: bit.ly/3MSxoa1 🏥CCB_VIB_KUL Department of Oncology - KU Leuven The Netherlands Cancer Institute Van Rheenen Lab Benjamin Simons

Ready to establish your own research group at the Hubrecht Institute for molecular and developmental biology? We’re seeking a tenure-track group leader to develop an innovative research line within our vibrant scientific community. Learn more & apply! hubrecht.eu/job/tenure-tra…

NEW! REVIEW Christoph Schneider & colleagues on tuft cells in the intestine, immunity and beyond Link: nature.com/articles/s4157… Read-only: rdcu.be/dVhSO

In case you are looking for an interesting/easy reading this weekend, how about some thoughts on in vitro human cell-based models cell.com/cell/abstract/… Cell Press Matthias Lutolf TAKEBE Takanori Laboratory

The GLP-1 drugs we've got now are just the beginning. The gut nutrient cell sensors ( a cellular instead of a peptide hormone target) have considerable potential. Brief thread by Hans Clevers on their new Science Magazine paper

Real fun collaboration between Hubrecht Institute and Institute of Human Biology labs on 'nutrient sensors' in the gut, with multiple interesting follow up studies (e.g. - apart from a convenient surface marker - why do all EECs specifically express an immune ckeckpoint?)

Only 2 weeks left to apply for our junior & senior group leader calls! Join us in Basel to do cutting edge basic and translational research on human disease. In a very collaborative environment, where you can leverage state-of-the-art human model systems and technology platforms.

📢We are hiring a postdoctoral researcher 📢 Are your curious about the mechanisms driving metastatic spread? Do you have *bioinformatics* skills to help us unravel these mechanisms? We (@Bergerslab, Colinda Scheele) may have your dream job @VIB_CCB! jobso.id/k7cp

If you really love your protein of interest commit to a tattoo Ardem Patapoutian

We updated our BindCraft preprint with lots of new exciting results! We release all our binder sequences and models, include more in silico analysis, novel design targets, and present AAV retargeting to specific cell types using de novo binders! biorxiv.org/content/10.110…

iFlpMosaics are now published Nature Methods. A compendium of novel genetic tools and related methods for inducing and analysing genetic mosaics in a high-throughput manner. nature.com/articles/s4159… Tweetorial 👇

Our first 2025 paper! We discuss in Nature Reviews Molecular Cell Biology how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer. Great work from our former and current tumor mechanobiology experts Vince Fiore & Jorge Almagro nature.com/articles/s4158…

We are searching for a Master's Student/Intern to join the group for 6-12 months to work on large-scale bioimage analysis of complex human model system data! Please send your CV to: [email protected] #IHB

Great pleasure to host shalev itzkovitz at Institute of Human Biology. Exciting talk & discussions on spatial transcriptomics of adult tissues. Including promising translational applications of using shed intestinal cells for longitudinal profiling of homeostatic and diseased cell states!

A new peptide, BRINP2-related peptide (BRP) administered pharmacologically, reduces food intake and exhibits anti-obesity effects in mice and pigs without inducing nausea or aversion. nature.com/articles/s4158…

We are searching for 2 talented MSc students to join the group! If you are interested in using advanced organoid models to study regulators of intestinal differentiation or nutrient uptake, please apply! go.roche.com/skt2b and go.roche.com/wf7hj Institute of Human Biology

New insights into the actions of GIP agonism vs. antagonism on food intake and body weight in mice from Timo Muller and colleagues #weightloss #obesity Nature Metabolism Timo Müller Matthias Tschöp nature.com/articles/s4225…

Modular integration of epithelial, microbial, and immune components to study human intestinal biology. Amazing team project with Rubén López Sandoval, Marius Harter, Qianhui Yu, Mike Nikolaev, Matthias Lutolf, Nikolche Gjorevski, and many others Institute of Human Biology biorxiv.org/content/10.110…

Thrilled to see #SAVANA out in Nature Methods🥳 SAVANA detects haplotype-resolved somatic SVs and copy number aberrations (SCNAs) and infers tumour purity & ploidy in clinical samples using long-read sequencing with or WITHOUT a matched germline control 👇nature.com/articles/s4159…