Reminder: submit your papers for inclusion in the newsletter, to the Google Form here!
mathematical-oncology.org/newsletter

More distraction: new #preprint we posted a little while ago biorxiv.org/content/10.110… looks at somatic copy number #evolution in #colorectal #cancer . Suggests a #CNA bottleneck adenoma->cancer, & thereafter CNAs experience #stabilising #selection , remarkably even in mets & chemo.

The Lise Meitner Excellence Program - great opportunity for female scientists who want to start their own group at an institute of their choice in the Max Planck Society.
Deadline is April 10 2024.

mpg.de/11946549/lise-…

I'm co-organizing Cancer Evolution: From Genome to Ecology, 8–10 May 2024, Wellcome Genome Campus, UK.

Listen to great speakers, including Nuria Lopez-Bigas, Raheleh Rahbari, Trevor Graham, Jose Tubio’s lab - Mobile Genomes and James DeGregori.

Abstract deadline: 12 March 2024.

…erences.wellcomeconnectingscience.org/event/cancer-e…

Thanks Arda Durmaz and Valeria Visconte! This is a great highlighting of our work. This was a fun project with a few surprises. There is much more to come soon on the evolutionary dynamics variant allele frequencies in healthy tissues.

This is essential for the future of UK science! It can't be underemphasised how much the foundations of it are eroding by current policies.

We are looking for two enthusisastic scientists to join our work on the evolution of ecDNAs in human cancers. Become part of the great Cancer Grand Challenges and join our team eDyNAmiC family.

Happy to chat any time. Please contact me and ask for details!

qmul.ac.uk/jobs/vacancies…

Wonder what the early history of administration is.

This application has to be submitted in 3 copies on solid rock?

At the department for Theoretical Biology MPI for Evolutionary Biology is looking for a PostDoc in Cancer Evolution mpg.de/21167917/postd… Please share!

You like digging into cool genetics data to understand cancer evolution?
We are recruiting a bioinformatics post-doc to work on oncogenesis in the oral cavity. This involves unique datasets on oral mucosa in diseased (oral cancer, Fanconi anaemia) and healthy subjects.

If you govern a country and the only solution to enact your envisioned policies is to withdraw from the European Convention on Human Rights, you might want to rethink your policies.

Just saying.

Our latest paper: measurement of cancer evolutionary dynamics at massive scale, using just a methylation array on bulk DNA. Find evolutionary dynamics strongly determine clinical outcomes in lymphoid cancers. Fab collab with Inaki Martin & Martí Duran-Ferrer, & led by Calum Gabbutt. A🧵⬇️

Really excited to share this new preprint! We have developed a somatic genetic clock to estimate the age of clonal organisms (e.g. plants) 🌱⏰🧬
biorxiv.org/content/10.110…

Ruxandra Teslo 🧬 throughout her life or only in old age?

Very happy to have our newest work available on bioRxiv .

Excited about this, as we combine ideas of somatic and species evolution.

Truly interdisciplinary joined work by Thorsten_Reusch LEi Yu Jessie Renton , Iliana Baums.

biorxiv.org/content/10.110…

Newly published paper from us: Mutant fixation in the presence of a natural enemy

nature.com/articles/s4146…

Sad reality, the few years I am here it has become noticeably worse.

The cost of living to income ratio in the UK is utterly insane (if you are not a banker).

theguardian.com/society/2023/n…

My response to any new administrative task: I feel thin, sort of stretched, like butter scraped over too much bread.

Join us in Cambridge!

2x group leader positions.

Particular interest: computational biology including AI

Core funded. Best start-up package you will get anywhere.

jobs.cam.ac.uk/job/43302/