Any newly minted PhD students interested in applying for a fellowship to work with me and Andrew Lewis in medicinal chemistry and chemical biology? Get in touch, DMs welcome!

Its out!! 🥳 Last piece of my work done at Tim Somervaille´s group CRUK Manchester Institute If you want to understand what else is helping LSD1 demethylase to bind chromatin and repress GFI1 target sites, you need to read this 👇👇 nature.com/articles/s4138…

Feeling blessed to have such a great team

Just out in Blood Journal: Super excited to share our findings that identify Strawberry Notch Homolog 2 (SBNO2) as a critical mediator for STAT3-driven hematopoietic malignancies by modeling STAT3 mutations and functional genetic screens. 1/ Full paper: doi.org/10.1182/blood.…

Not our normal place to publish….. but this story in the Daily Express highlights some of the exciting albeit preliminary results for patients we are seeing in our fantastic collaboration with CellCentric and clinicians across the UK & EU & lab work from Luciano Nicosia

The very first experiment is underway in our new building!

Our laboratory is set up in the new building with panoramic views across Cheshire and Lancashire from the fifth floor.

Fantastic write up area for our post docs and students with more panoramic views this time across the Peak District.

Want to use deep learning for image analysis but lack the coding skills? We introduce DELiVR, a game-changer in brain-wide cell analysis. No coding required, our Fiji Plug-in does the magic. Hats off to Doris Kaltenecker, Rami, @[email protected]! 🧵👇🏼 1/n biorxiv.org/content/10.110…

If you are interested in AML and microenvironment, join us at The University of Manchester Division of Cancer Sciences Postdoc position available in my group (extended deadline: 22nd October 2023) More details at the link below 👇 Please RT🙏 #postdocposition #leukaemia

📢MRC funded PhD scholarship available in our lab Division of Cancer Sciences The project will explore immunotherapy as promising therapeutic approach in acute myeloid leukaemia! Apply through the link below👇 (deadline 10 November 2023) bmh.manchester.ac.uk/study/research… #leukaemia #PhDposition

MRC funded PhD scholarship available in my lab! Please see details below and get in touch if interested 🙂 Please RT😇 #PhDposition

Our group is delighted to be funded by Leukaemia UK This grant will allow us to investigate the role of the microenvironment in supporting AML! If you are interested in this project, please apply for the postdoc position available in our lab! Deadline 22/10 jobs.manchester.ac.uk/Job/JobDetail?…

Online Now: Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies dlvr.it/SzBhbS

Our work describing the preclinical, molecular, and encouraging early-phase clinical data of the EP300/CBP bromodomain inhibitor CCS1477 (also known as #Inobrodib) in #AML and #MultipleMyeloma is out in Cancer Cell. cell.com/cancer-cell/fu… Tim Somervaille CRUK Manchester Institute CellCentric

We are excited to share pre-clinical and some early clinical data for inobrodib which looks encouraging for patients with blood cancer cell.com/cancer-cell/fu…

Onto Dr Bettina Wingelhofer Bettina Wingelhofer from CRUK Manchester Institute The University of Manchester discussing enhancers in #AML #YoungEHA #BSH2024

Catching up with my unofficial supervisor Bettina Wingelhofer and lab colleague Sara. #EHA2024 #MDSsm #leusm #MPNsm Division of Cancer Sciences

Gorgeous gorgeous #Manchester night at #EHA2024 ! Tim Somervaille Dan Wiseman Simona Valletta Bettina Wingelhofer Division of Cancer Sciences

I had a fantastic time in Madrid at #EHA2024 ! Amazing science and food😎 It was great to catch up with old friends and establish new collaborations✅ See you next year in Milan! European Hematology Association