Our latest paper - work led by Astrid De Roover and Silvia Monteagudo - is out in JCI insight! “Hypoxia induces DOT1L in articular cartilage to protect against osteoarthritis" insight.jci.org/articles/view/… – a team story to share KU Leuven UZ Leuven Dept of Development and Regeneration - KU Leuven #osteoarthritis 1/9

Our last paper "Hypoxia induces DOT1L in articular cartilage to protect against osteoarthritis" has been highlighted in Nature Reviews Rheumatology! Rik Lories Astrid De Roover Ana Escribano Chahrazad CHERIFI Frederic Cailotto Lies Storms leire casas

Finally out! Astrid De Roover Rik Lories Chahrazad CHERIFI Dept of Development and Regeneration - KU Leuven

Orthopaedic Research Society Bravo Astrid De Roover , learn a lot!

Astrid De Roover winning osteoarthritis foundation mobility grant. Congratulations to supervisor Silvia Monteagudo

For our Cartilage Biology & Pathology GRS/GRC attendees next week - we have a fantastic program full of amazing science, and we are setting up afternoon outings to visit these local attractions: Walled city of Lucca Bio-Organic Winery Grotto del vento - Wind cave See you soon!

Are you curious about our paper that has just been awarded as "Best publication of the year" by OARSI? Rik Lories OARSI Osteoarthritis and Cartilage Journals Dept of Development and Regeneration - KU Leuven Thank you to the people that nominated this work and made the final selection! You can know the story here👇

Proud to receive the Osteoarthritis and Cartilage Journals basic science paper of the year reward for the team with Silvia Monteagudo You can read it at tinyurl.com/3w64vtsd - this paper took us from cartilage to heart and brain! Dept of Development and Regeneration - KU Leuven

What is new on #osteoarthritis? ▶️ OA is linked to deficient methylation on H3K79 ▶️KDM7A/B demethylase regulated H3K79 methylation status ▶️KDM7A/B inhibition counteract H3K79me deficiency -> protection against disease 🔗 bit.ly/3FwMOx1

Happy to share our new paper on #epigenetics in #osteoarthritis just published in @ardbmj with lead authors Reem Assi Chahrazad CHERIFI Rik Lories Silvia Monteagudo from wynterborne @kuleuven in collaboration with LUMC Leiden tinyurl.com/2s47pcup (1/10)

Very excited to present our latest findings on #epigenetics in #cartilage and #osteoarthritis, just out in @ARD_BMJ Hard 💪and fun🥳 team work, especially with Chahrazad CHERIFI Reem Assi and Rik Lories Rik Lories at Dept of Development and Regeneration - KU Leuven. Check it out here!! 👇

First time presenting my research on Kindlin-2! Grateful to do it in SER OARSI 2023 in A Coruña! It was easy with the support from THD lab colleagues Nuria Viudes Sarrión @Rocio_cv Ana Escribano Astrid De Roover

Dr. Rik Lories, Professor KU Leuven and Chair of the Division of Rheumatology UZ Leuven, speaker for the 3rd International Workshop on the Epigenetics of #OA, will present on Day 2 of the event, Sept 5, 2024, in Session 6: Pharmacological Modulation of the OA Epigenome. His talk

We hope this research brings us one step closer to finding a disease-modifying therapy for osteoarthritis. Stay tuned as we explore new ways to target the Wnt-IGF1 axis in future therapeutic approaches. 13/14

Unlocking a Detrimental Role of IGF1 in Osteoarthritis: A New Target for Therapeutic Intervention? | Research Communities by Springer Nature communities.springernature.com/posts/unlockin…

New online! Wnt-induced IGF1 drives OA go.nature.com/3ZEE6GD

Thrilled to share I’ve successfully defended my PhD thesis; Inhibition of histone demethylases to restore H3K79 methylation in OA.” 🎉 Huge thanks to my supervisors, Silvia Monteagudo & Rik Lories, and to my jury Cristina Ruiz Romero, Jessica Bertrand, Ludo Van Den Bosch and Jan Cools!