Thought for the day

'..cause it's not about the money'

Carl Sagan explains how the Ancient Greeks, using reason and math, figured out that the Earth isn't flat, more than 2,000 years ago. Amazing.

Full video and a bunch of Sagan quotes here: stevestewartwilliams.com/p/top-12-carl-…

🤔Who here is interested in expanding their knowledge of ChimeraX ?
What specific areas are you eager to explore?

❤️🔁 is greatly appreciated.

Kristian Andersen publishes all correspondence with NYT journalist Don McNeil after the latter accused KA of misleading him

Turns out McNeil is the one misleading and misrepresenting

The list of apologies KGA/PO authors need is getting very long now

medium.com/@K_G_Andersen/…

#AcademicTwitter You and your PI attending your first conference together! #phdvoice #phdchat

Today’s CPI report shows meat & poultry are among the highest items pushing inflation.

Maybe that's because just 4 companies now control processing of 80% of beef, nearly 70% of pork, and almost 60% of chicken.

Without competition, corporations can get away with price gouging.

Thread: Want to think out loud about what I've seen and experienced since joining NPR a few years ago. I was hired during NPR's 'North Star' era when diversity was established as a priority. I'm an aging rural white man (58 years old). Never graduated college. Didn't see NYC...1/

BREAKING: What do you notice about this video of Arizona supreme court?

As they banned abortion, Glenn Youngkin did something just as awful... almost NO ONE in the media is talking about it.

Last night he effectively VETOED the right to BIRTH CONTROL. But he did so in a sneaky…

Perceptive piece by Russell Baker Russ Baker (realrussbaker on Threads), founder + Editor in Chief of courageous and spunky WhoWhatWhy WhoWhatWhy, explaining vicious attack by hack writer Paul Thacker upon Dr. Allison Neitzel, physician (AMA's version). Please read it + support this critical journalism.

whowhatwhy.org/science/contri…

See how ridiculous you sound 🤷‍♂️

Praying for the Rapture on Monday! 🙏

Tonight, Donald Trump is holding a billionaire fundraiser to pay his mounting legal bills.

Here are some of the scammers, racists, and extremists funding Trump’s failing campaign.

🧵

It starts with insurance rates. Then comes uninsurability. That hits mortgages. Then home values fall, hitting local economies. Hit hard enough, it becomes systemic, nationwide.

We are likely seeing the beginnings of this trajectory.
bloomberg.com/news/articles/…

So what should one do?
1. Pre-process your #scRNAseq FASTQ files w/ a program that outputs separate matrices (see biorxiv.org/content/10.110…)
2. 'Integrate' them via biophysical modeling rather than w/ heuristics (e.g. biorxiv.org/content/10.110… w/ Maria Carilli et al.) 15/15

The difference in 10x Genomics' Cell Ranger's default between version 6 and 7 is discussed in this thread, but it's such a big deal that it's worth its own thread.

tl;dr: in v7 Cell Ranger changed how it produces the gene count matrix leading to a huge difference in results. 1/

Instead of going into debt so I can daily drive a pickup truck in the city, I occasionally pay $20 to rent a trailer for the day.

What Musk and Beff Jezos aren't saying is that Silicon Valley is OVERRUN by human-extinctionist ideologies! The dominant visions of our future among the tech elite, espoused by both Musk and Beff, ARE EXTINCTIONIST. A 🧵 on my newest article for Truthdig: truthdig.com/articles/team-…

1. Much human genetic variation is phenotypically meaningless. Why? Cooperative genes are locked in a forever war w/ selfish genes. The cooperative genes have won most battles but now our genomes are littered with the dead & decaying bodies of a million selfish genes. 🧵