🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Our study led by @RomitB_MD in REPRIEVE Trial shows that among people with HIV, clonal hematopoiesis risk factors include age, smoking, low CD4 nadir, North American origin, and non-Hispanic ethnicity ashpublications.org/bloodadvances/… Blood Advances

Our study is out nature. We identify non-lipid risk pathways for coronary artery disease using pooled CRISPR-interference for 2,285 genes at GWAS loci. With an amazing team we identified the genetic risk pathways for CAD that act in endothelial cells. nature.com/articles/s4158…

Delighted to write the editorial with Aniruddh Patel contextualizing these exciting preliminary findings in JACC Journals paper: sciencedirect.com/science/articl… editorial: sciencedirect.com/science/articl… STAT coverage: statnews.com/2024/02/12/sou…

Excited to share our work by MGH IM Residents Roger Zou & with Aniruddh Patel examining CV polygenic risk scores derived in the general population among those living with HIV in REPRIEVE Trial on subclinical athero. A CAD PRS associates w presence of any, severe, & high risk plaque.

The South Asian American experience is highly varied across the US. Did you know 🤔: 👉 OurHealth participants to date span *35* US states! ☺️ ourhealthstudy.org

Excited to share our study investigating the genetics of combined lipid patterns led by Tom Gilliland Jacqueline Dron, PhD! ahajournals.org/doi/10.1161/CI… Circulation Research [1/8]

Polygenic risk scores are increasingly being deployed. Despite reasonable correlation of scores, a classification of high polygenic risk for a trait varies widely across scores. Our study led by A. Misra & with Aniruddh Patel evaluates this issue, & proposes an integrated

Are you an MD student interested in research? Would strongly consider applying for the Sarnoff Foundation Fellowship. Scientific immersion with *unparalleled* longitudinal mentorship & exceptional peer network career-long. sarnofffellowship.com My biggest regret in med school was

Out today in European Society of Cardiology Journals the new ESC 2024 GL for elevated BP and hypertension led by co-chairs John William McEvoy and Prof Rhian Touyz. Honored to serve as a task-force co-ordinator and writing comittee member alongside Rosa Maria Bruno. #ESCCongress Thread/

If you’re at European Society of Cardiology #ESC2024 #ESCCongress2024 Check out 2 presentations from our group: Aug 30 14:41 - ECG artificial intelligence to detect prevalent CAD Shino Kany Aug 31 10:00 - CAD polygenic risk score and outcomes after coronary angiography Kelvin Supriami

Fantastic nature News Feature by anil oza- Why does heart disease affect so many young South Asians? Highlights our ambitious goals with OurHealth & others like MASALA Study. nature.com/articles/d4158… 💜 ourhealthstudy.org 💜 Sadiya Khan Alka Kanaya @NammiKan

Excited to share our latest manuscript in Nature Genetics! Utilizing high-resolution genetic data imputed with a population-matched reference panel, we uncovered causal genetic variants for a wide range of human traits over 200K participants from Japan (1/20) nature.com/articles/s4158…

Our preprint led by Mass General Vascular resident @AlyssaFlo and with Aniruddh Patel deriving & evaluating a new polygenic risk score for peripheral artery disease across Mass General Brigham Biobank UK Biobank AllofUsResearch. Comparable performance to diabetes and smoking!

Thank you again for the kind invitation & congrats on a massive turnout CCRNMD - nearly 450 people! Great talks from Alka Kanaya Aniruddh Patel Khurram Nasir highlighting the landscape of #SouthAsianCVD, PRS, role of Lpa & CAC testing

Among British Pakistani & British Bangladeshi individuals, partitioned T2D polygenic load for insulin deficiency & lipodystrophy was higher than white European individuals & predisposed to faster progression to T2D & complications nature.com/articles/s4159… Nature Medicine

Applications are now OPEN for the 2025 Human Genetics and Genomics GRC and GRS! 🎉🧬 📅 GRS: July 5-6, 2025 📅 GRC: July 6-11, 2025 📍Portland, Maine Cal Liao and I are co-chairs for the GRS, with Shamil Sunyaev and Eimear Kenny as the GRC chairs👀 Links to apply below 👇

We are excited to share our latest work, "Genetic Predisposition to Low-Density Lipoprotein Cholesterol and Incident Type 2 Diabetes," now published in JAMA Cardiology, led by the brilliant undergrad Akshaya Ravi! 🎉 jamanetwork.com/journals/jamac…

Individual polygenic risk scores for the same trait can yield different results due to various derivation differences. Our study led by A. Misra & w Aniruddh Patel demonstrates how successive score integration can improve accuracy & stability nature.com/articles/s4146…

Our study led by Alyssa M. Flores, MD & with Aniruddh Patel describes a new peripheral artery disease PRS. Predictive capability for incident PAD is comparable to CKD & DM2. Among those with PAD, it also associates with major adv limb events jamanetwork.com/journals/jamac… JAMA Cardiology

A new polygenic score estimated peripheral artery disease (PAD) and identified more cases of incident PAD when added to screening criteria. ja.ma/4jcVF88 Alyssa M. Flores, MD Aniruddh Patel Pradeep Natarajan Tiffany Bellomo