🔔 Congratulations to Malvina Pizzuto for leading this cool project on inhibitions of Casp4 by Cardiolipin 👏👏👏 it was a lot of fun to work together with Malvina and Mercedes from Inflammasome Lab UQ News on this project!!!!! 🤩💃

New review from our lab. Kudos to PhD student Seb Grant. 10 things you wish you knew about inflammatory caspases: a holistic review of their biochemistry, activation, and signalling - Journal of Biological Chemistry jbc.org/article/S0021-…

Fantastic new paper by Reese Richardson et al. "The entities enabling scientific fraud at scale are large, resilient, and growing rapidly." An enormous amount of work showing the extent of coordinated scientific fraud and involvement of some editors. pnas.org/doi/10.1073/pn…

NCCR AntiResist, “New approaches to combat antibiotic-resistant bacteria”, is recruiting a Scientific Officer (80-100%) biozentrum.unibas.ch/open-positions… Biozentrum, University of Basel #Biozentrum #Basel #research #science #basel #job #recruiting #careers #Scientific #Officer #NCCR #AntiResist

Kicking off the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors organized by our department in Lausanne! Broz Lab Fabio Martinon RebsamenLab Faculté de biologie et de médecine (inactif)

2nd day of the PRR kicks off with more great talks from all speakers including our own Jakub Began. Department of Immunobiology at UNIL Immunobiology2025@UNIL

Postdoc – Role of signal transduction in E. coli bacteriophage infection and defence - Jenal lab (100%) biozentrum.unibas.ch/de/open-positi… Biozentrum, University of Basel University of Basel #Biozentrum #Basel #research #science #joboffer #hiring #postdoc

Do not miss this! #inflammazoom is back in October 🎉 with James Murphy from WEHI and Jonathan Maelfait from VIB Ghent we are back with some really 🔥 stories!

It’s DIB day! The annual conference for our department Department of Immunobiology at UNIL. It’s a lovely day (and view!) at the Lausanne Olympic museum exchanging with our colleagues. Plus a stellar presentation on NINJ1 by our own Elliott Bernard 🔬!

Postdoc opportunity in Alexis A. Jourdain !

Thanks to authors of the news and views for Alexandra Boegli 's NLRP6 story, highlighting the disruption to homeostasis as the activation trigger. link.springer.com/article/10.103…

Happy to announce that our paper is finally out! Thanks to Broz Lab and co-authors 🥳 the NLRP6 inflammasome is activated by sterile- or pathogen-induced endolysosomal damage The EMBO Journal

The NLRP6 inflammasome is activated by sterile or pathogen-induced endolysosomal damage link.springer.com/article/10.103… The EMBO Journal Broz Lab Alexandra Boegli

Beautifully written news and views article by Weber and Rosenstiel about our new NLRP6 story that I was honoured to spear-head 👩‍🔬🔬Perfect for a quick summary!

#InflammasomePower! #EveryCellIsAnImmuneCell! #MysterySolved! Broz Lab Alexandra Boegli &co show The EMBO Journal that in intestinal epithelial cells NLRP6 senses endosomal damage to trigger GSDMD-dependent IL1 release & pyroptosis against bacterial invasion! link.springer.com/article/10.103…

Congrats 🥳, Broz Lab and Alexandra Boegli on your elegant study! @PhilipCRosensti were very happy to discuss and highlight the important new insights into #inflammasome and infection biology it offers!

Our latest work from Broz Lab and led by Alexandra Boegli is out now in The EMBO Journal. Check out our findings on how the intestinal #inflammasome NLRP6 senses lysosomal damage to trigger pyroptotic cell death. embopress.org/doi/full/10.10…

Broz Lab Elliott Bernard Ella Hartenian Current Biology You are on 🔥!!

🎩 Congratulations to Fabienne Estermann on her marvellous new hat! 👩‍🔬 Fabienne's PhD thesis was "Of Resistance Mechanisms and Prophage Activation: Characterizing the Behavior of Pathogens in Clinical Contexts". All the best, Fabienne, we will miss you!

Congratulations to (former!) postdoc Ella Hartenian on launching her career with a prestigious SNF Ambizione grant at the Department of Immunobiology at UNIL studying how hosts respond to viral infection in her own lab here at University of Lausanne.