The first study to evaluate treosulfan with ATG and PTCY reveals treosulfan's efficacy and safety in stem cell transplantation. Treo-based conditioning shows better overall survival versus busulfan in #mds patients. Read more: ow.ly/1tzN50Sx6gW

Are the #CARTcells therapy studies from the “Real World” truly real? The study by Ahmed et al. addresses the access gap and discusses the critical findings around minority status, income and proximity to a CAR-T center. Read the full article: astctjournal.org/article/S2666-…

In this largest study to date of patients from the United States and Canada with FLT3-ITDmut+ #AML, disease status of first complete remission at the time of #alloHCT was associated with better clinical outcomes. ow.ly/75HH50SBx30

This randomized trial study showed that the application of platelet gel-containing dressing in ulcerative skin #cGVHD is safe. Platelet gel-containing dressing is a curative approach for ulcers of skin cGVHD. Read more: ow.ly/Y8Qv50SBx5r

A secondary data analysis study shows that there is no significant association between obesity measured by waist-to-hip ratio and progression-free survival or overall survival in MM patients undergoing #HCT. Read more: ow.ly/1uvC50SBx86

Recent NMDP data shows a decline in bone marrow (BM) quality. To address this, the NMDP Marrow Alliance was formed in April 2021 to improve BM collection centers and set best practices. This paper drafts guidelines for delivering high-quality BM products. ow.ly/LqEq50SBxnI

In a retrospective JSTCT study, association between CMV reactivation measured by pp65 antigenemia and relapse of the myelodysplastic syndrome after #HCT was dependent on the bone marrow tumor burden at transplant.astctjournal.org/article/S2666-…

A study demonstrates cairo severity grading system may be superior in predicting ICU admissions and intubation when compared to the EBMT severity grading system. Read more: astctjournal.org/article/S2666-…

A retrospective analysis of an academic formal #HCT survivorship program with primary and specialty consult components concluded that the primary HCT team was critical to the success of the survivorship program. Read more: astctjournal.org/article/S2666-…

A study supports the safety and efficacy of bendamustine LD for brexu-cel. Their data also suggest that bendamustine LD can facilitate #CART cell expansion in the absence of fludarabine. Read the article here: astctjournal.org/article/S2666-…

#HSCT remains a key therapy for tyrosine kinase inhibitor(TKIs) resistance or advanced-stage chronic myeloid leukemia. This long-term follow-up analysis finds the molecular or cytogenetic response prior to HSCT impacts prognosis. astctjournal.org/article/S2666-…

The meta-analysis of real-world studies of axi-cel versus tisa-cel in relapsed/refractory DLBCL finds that axi-cel significantly improves responses and progression-free survival, while tisa-cel significantly reduces higher-grade CRS and neurotoxicity. ow.ly/Q1sx50SNJ6z

This brief article goes over how the pediatric stem cell transplant recipients have suboptimal sleep duration and quality. Sleep quality, depression, and quality of life were lowest at day +14 and +30. Read more: ow.ly/z2A350SNJ7g

The August issue of 'Transplantation and Cellular Therapy' is now available online: astctjournal.org/current Elsevier Hematology

A retrospective study of NDMM patient outcomes following auto-SCT for three decades found that outcomes improved following auto-SCT in NDMM patients, including those with high-risk disease. astctjournal.org/article/S2666-…

A total cost of care was compared for letermovir prophylaxis versus preemptive therapy. For high-risk pts, letermovir decreases total cost of care through day+180 and for standard-risk pts, letermovir reduces inpatient cost of care through day+180. astctjournal.org/article/S2666-…

Discover the top-cited articles of 2024 in Transplantation and Cellular Therapy. These selections highlight key advancements in hematopoietic cell transplantation and related therapies. Access the collection here: astctjournal.org/2024-top-cited… #HCT #GVHD #Lymsm

A study on hemophagocytic lymphohistiocytosis gene variants in severe aplastic anemia (SAA) suggests that there is no need for special HCT considerations for SAA patients carrying HLH variants. Read more: astctjournal.org/article/S2666-…

This ASTCT-led survey highlights the trends in and patterns of U.S. physicians’ practices regarding post-CAR-T surveillance, diagnosis of CAR-T failure, and management of relapsed disease. Read the full practice guidelines survey here: ow.ly/gTUk50SWmBI

A multicenter retrospective analysis of adults with RRMM who received previously collected CD34+ stem cell boosts post-#CARTcell therapy shows that these boosts can serve as an effective rescue for post-CAR T cytopenias and related complications. ow.ly/vHjA50SWmCj