4x4 rotation collage of c5 symmetric synthetic protein backbones I made using rfdiffusion -> pymol+

They look even cuter as space-filling models

life is the rage against entropy

codex doing some protein troubleshooting

c7 symmetric diffusion in action, unconditional backbones. One-shotted with codex using subseq.bio rfdiffusion -> pymol+

wow.... OpenAI does not like my research

has anyone gotten symmetry to work using RFdiffusion3 ? even the doc examples are not working for me

🔗New: Pre-signed URL's allow for quick sharing of datasets, jobs, or any individual file within them. Anyone with the links can download the data within the expiration window. Available on Web, API, and MCP tools.

New MCP documentation👇 Includes configs for cursor, claude code, and codex. Many improvements have been made to the mcp server since release, you should give it a try. AI-powered protein design is here.

4 different sars-cov-2 binders via rfdiffusion3

📰Introducing subseq Blog! subseq.bio/blog First blog post: Intro to GROMACS for Protein Design subseq.bio/blog/intro-to-…

c5 symmetric barrel

🗞️New Project Viewer! A new UI page lets you see all assets associated with a project for better organization.

Finally you can construct custom pipelines! 6 Step Example: - rfdiffusion (generate backbones) - ligandmpnn (solve sequences) - esmfold (generate candidate structures) - gromacs (MD simulations) - pymol+ (render animations / images) - Utility (analysis, final report generation)

New icons and collapsible nav bar give more space for protein design.