🎯 Looking forward to present our work at EMBO Nuclear Receptors: No Disease is Safe to be held from Sep 23 - 26, 2024 at beautiful Cavtat, Dubrovnik, Croatia 🪸💦

as endocrine resistance remains a major challenge in the treatment of breast cancer, alternative therapeutics are needed. Check out our latest bioRxiv spearheaded by emira visser, using ER/14-3-3 molecular glues as new putative treatment strategy
doi.org/10.1101/2024.0…

10 years after discovering the first cancer arising from chromatin as opposed to genetic variants (pubmed.ncbi.nlm.nih.gov/24553142/) a new study provides further evidence that cancer development can arise solely from chromatin variants. pubmed.ncbi.nlm.nih.gov/38658752/

📢📢Registration is OPEN for #EMBOnuclearReceptors !!
Nuclear Receptors: No Disease is Safe
23 – 26 September 2024 | Cavtat, Croatia

meetings.embo.org/event/24-nucle…

📢Save the date! EMBO Workshop
Nuclear Receptors: No Disease is Safe
23–26 September 2024 | Cavtat, Croatia

details on program and invited speakers will be announced asap 😀
Sign up below, so that you get the latest updates!
👇👇👇
coming-soon.embo.org/w24-114

From the November issue—
#TransposableElements Are Co-opted as Oncogenic Regulatory Elements by Lineage-specific Transcription Factors in #ProstateCancer , by GiacomoGrillo, @matlupien et al.
bit.ly/3sJ25aX
Princess Margaret Cancer Centre University of Toronto Ontario Institute for Cancer Research (OICR)

Today we introduce you to Nick Tobin , Chair of the Scientific Committee for the CCE #SummSchool23 and Petra Oberrauch, leader of the Organising Team of the CCE Summer School and member of CCE’s Operational Board.

Read more about them ➡️ cancercoreeurope.eu/meet-the-peopl…

🗞️Available to read online!

Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1–NDRG1 deregulation

🔓buff.ly/3R7voNZ

Jelle Wesseling
#BCSM #Proteomics
#ERα #Metastasis

Deadline for abstract submission is TODAY! Come join us in Eindhoven for the Dutch Endocrine Meeting 2024, feb 8-9!

Register now for the Dutch Endocrine Meeting, feb 8-9 2024! Amazing speakers, great science, lots of opportunity to network and meet your colleagues!

congres.nve.nl/conference/dut…

Delighted to serve on the board of directors of Cancer Core Europe, and contribute to our joint mission of improving the treatment of patients with cancer, through stimulating excellent research and collaboration with our European partners

Another new pre-print from our team on bioRxiv, by Stacey Joosten et al! We show ER / chromatin profiles as tremendously variable among breast cancers. What are the biological and clinical implications thereof? Any associations with risk SNPs? 🤔
biorxiv.org/content/10.110…

Proud of our latest study highlighting the glucocorticoid receptor's (GR) key role in primary cancer biology, especially in determining ER-positive breast cancer subtypes and patient outcomes. Full details in the thread 🧵👇 EMBO Mol. Medicine The Netherlands Cancer Institute UMCU_CMM embopress.org/doi/full/10.15…

Online today! Luminal #BreastCancer identity is determined by loss of #GlucocorticoidReceptor activity

By Stefan Prekovic Zwartlab_NKI & colleagues The Netherlands Cancer Institute UMCU_CMM

🗞️ #openaccess : doi.org/10.15252/emmm.…

Glucocorticoid Receptor acts as tumor suppressor in ER+ #breastcancer , highlighting distinct biology between Luminal A and B tumors. Check out our latest paper in EMBO Mol. Medicine, spearheaded by Stefan Prekovic! UMCU_CMM The Netherlands Cancer Institute Oncode Institute KWFKankerbestrijding
doi.org/10.15252/emmm.…

In a subset of #BreastCancer metastases ER is lost. Do they become genuinely ER-negative, on proteome level? And which pathways are altered when ER is lost? Check out our latest paper in Molecular Oncology, spearheaded by Isabel Mayayo-Peralta!
doi.org/10.1002/1878-0…

Piet Borst reflects on his 50-year career in biomedical research as he accepts the 2023 #LaskerAward for Special Achievement in Medical Science.
The Netherlands Cancer Institute #LaskerLaureate #Lasker2023

Ever wondered how p300 is degraded? No, it’s not through ubiquitination….Check out our latest co-production with the Christine Blatter lab, now published in LifeScienceAlliance!

Piet Borst is a true force of nature, tremendously gifted scientist and inspiration to all, a mentor of mentors for many decades (and continuing to do so!). Congratulation Piet!! The Netherlands Cancer Institute
Absolutely wonderful news!

Congratulations to Piet Borst for receiving this prestigious award! Well-deserved 🎉