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Do hepatic stellate cells regulate liver functions besides promoting fibrosis ? The answer is yes. In this paper published today in nature, we show that they play a key role in ZONATION, an important feature of a normal functioning liver. rdcu.be/ediAk

Original Article Phosphoproteomics delineates hepatocellular carcinoma subtypes and pinpoints therapeutic targets Zhang et al. #LiverX tinyurl.com/594npjxa

Super happy to share our new review in Nature Reviews Nephrology: nature.com/articles/s4158… Kidney Precision Medicine Project MS_Imaging Imaging MS Society UT Health San Antonio Research Pacific Northwest National Laboratory

Original Article Spatial single-cell proteomics landscape decodes the tumor microenvironmental ecosystem of intrahepatic cholangiocarcinoma Hong et al. #LiverX tinyurl.com/45dtaxf5

In HCC, eIF3f|ACSL4 was shown to promote tumour malignancy by promoting fatty acid biosynthesis, with its targeting increasing anti-PD-1 efficacy 👉journal-of-hepatology.eu/article/S0168-… Journal of Hepatology

Integral-Omics: Serial extraction and profiling of metabolome, lipidome, genome, transcriptome, whole proteome and phosphoproteome using biopsy tissue buff.ly/wURE5YB (ACS Analytical Chemistry Journals)

Very happy and proud to see our work published in Metabolism! metabolismjournal.com/article/S0026-… We thank all our collaborators and especially all the patients who contributed to the study. Thank you Zoe Hall for all the support since day one!

Excited to present our work at #EASLCongress (THU-036-YI). See you tomorrow on the Track Hub 2 - Basic science at 1pm to check how we use #massspecimaging and IMC for metabolic profiling of #liver fibrosis. Special thanks to our collaborators and funders Zoe Hall Metabolism, Digestion & Reproduction

Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism dlvr.it/TKdwwC

🚨 New in Nature Communications: We present a spatial multi-omics platform that maps the metabolome, lipidome, and glycome from a single brain section. Combining MALDI imaging with our computational tool Sami, we reveal metabolic diversity in health and Alzheimer's disease. 🔗

Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution go.nature.com/43rCoet

I’m happy to share that our scCellFie manuscript is finally on bioRxiv — a project that was an amazing opportunity to return to my roots in metabolism! We infer metabolic activity from single-cell & spatial transcriptomics 🧬 Read the pre-print here👇 📄 doi.org/10.1101/2025.0…

Label-free multimodal optical biopsy reveals biomolecular and morphological features of diabetic kidney tissue in 2D and 3D | ⁦Nature Communications⁩ nature.com/articles/s4146…

Cell-intrinsic metabolic phenotypes identified in patients with glioblastoma, using mass spectrometry imaging of 13C-labelled glucose metabolism go.nature.com/4jWzft2

Glad that we are up and running in the PROMISE Trial at Imperial Hepatology Metabolism, Digestion & Reproduction, and looking forward to exploring the impact of #FMT in #cirrhosis

Great Exhibition Road Festival is nearly here! We will be exhibiting "Your Liver: The Inside Story" in the Future Medicine Zone. Aleksandra Gruevska Evangelos Triantafyllou Georgia May Lorentzen Metabolism, Digestion & Reproduction NIHR Imperial BRC Imperial Hepatology British Liver Trust See you there! greatexhibitionroadfestival.co.uk

It was a brilliant first day at the Great Exhibition Road Festival teaching all there is to know about the #liver! Gearing up for even more fun today! 🧫🧪🔬🩺 Evangelos Triantafyllou Zoe Hall Aleksandra Gruevska Georgia May Lorentzen Metabolism, Digestion & Reproduction

Imperial Hepatology Zoe Hall Aleksandra Gruevska Georgia May Lorentzen Metabolism, Digestion & Reproduction It’s day two of the Great Exhibition Road Festival and we are ready to do it all again 👩‍🔬🧑‍🔬 Check out what is on today (12-6pm): greatexhibitionroadfestival.co.uk