Communicating clocks shape circadian homeostasis science.sciencemag.org/content/371/65…

New paper from Sehgal Lab. Congrats to first author Yool Lee Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle advances.sciencemag.org/content/7/7/ea…

Bottom line: BMAL drives a rhythm in TRPM7 expression that results in oscillating magnesium levels, resulting in rhythmic ABCB1 activity, and rhythmic xenobiotic efflux. Shirley Zhang's schematic making has improved - compare this paper to the dead chickens in the 2018 paper:

DST is bad, perma-DST is worse. Restore permanent #StandardTime for public health. ncbi.nlm.nih.gov/pmc/articles/P…

and here is our simple web browser developed by Patricia Losada to look up the expression of your favorite gene in the human brain vasculature and in AD twc-stanford.shinyapps.io/human_bbb/

Assistant/Associate Professors in Biochemistry: The Department of Biochemistry, a basic science department of the Emory University School of Medicine, is seeking to hire Assistant/Associate Professors (tenure-track).

Technician - check Equipment - check Reagents - check Ok! The lab is ready for postdocs! shizhanglab.com

Please RT! Tenure track sleep and circadian biology position open at Penn Medicine, some of the best in the business. .CC Amita Sehgal Joseph Takahashi apply.interfolio.com/111010

Congrats to Yongjun for publishing the last of the eLife articles before the "publish everything" experiment begins! Ecdysone acts through cortex glia to regulate sleep in Drosophila doi.org/10.7554/eLife.…