Importance of #dengue human challenge studies to answer key questions in dengue.

Despite individuals having neutralising Abs to DENV1 following vaccination, they were not protected when challenged.

#vaccines
thelancet.com/journals/lanin…

Bali advises foreign tourists to get dengue fever jabs amid rising cases straitstimes.com/asia/se-asia/b…

Today is #WorldHealthDay .

This year’s theme, #MyHealthMyRight , is a reminder of 1) how much progress we have made, but also 2) how far we have to go to make sure health is truly a right enjoyed by all.

#WorldHealthDay 2024
#ProudtobeWHO

Hey #dengue researchers - we are building a community resource page for DENV surveillance.

Please respond with links of protocols, pipelines, resources that we should include:
- sequencing
- PCR
- bioinformatics
- case data aggregation
- sero assays
- other useful tools

PAHO/WHO calls for collective action in response to record increase in #dengue cases in the #Americas paho.org/en/news/28-3-2…

Despite herculean efforts in vector control, dengue cases continue to surge. Vaccination would boost population immunity…unfortunately we still await licensing of Qdenga in Singapore (although already approved by EMA and several neighbouring countries). straitstimes.com/singapore/over…

Happy to share our latest preprint, entitled 'Application of chimeric antigens to paper-based diagnostics for detection of West Nile virus infections of Crocodylus porosus – a novel animal test case'. biorxiv.org/cgi/content/sh… More great stuff coming from the Peters' Lab!

Updates on this year's Asia Dengue Summit. Join us in KL, Malaysia. Keynote by Jeremy Farrar. Speakers include Henrik Salje Cameron Simmons Sophie Yacoub Shirin Kalimuddin Giri Rajahram and many others.

Protective Role of NS1-Specific Antibodies in the Immune Response to Dengue Virus through Antibody-Dependent Cellular Cytotoxicity
academic.oup.com/jid/advance-ar…

What would happen if you got vaccinated against the same antigen over and over again? In The Lancet Infectious Diseases, we now report on a hypervaccinated individual from Magdeburg (HIM) who received 217 vaccinations within 29 months against SARS-CoV-2. 👇 1/19 thelancet.com/journals/lanin…

Severe disease during both primary and secondary dengue virus infections in pediatric populations
nature.com/articles/s4159…

Over the last twenty years, reports of dengue have increased tenfold. Roughly half of the world's population is now at risk.

But what's behind the increase? Well, it's complicated... ⤵️🧵[1/5]

Epidemiological Alert PAHO/WHO - Increase in #dengue cases in the Region of the Americas - 16 February 2024
paho.org/es/documentos/…

There's an interesting new JCI paper published looking at the effects of switching vs. using the same arm for vaccine doses:
jci.org/articles/view/…

A thread🧵

Do join us on 5-7 June in Kuala Lumpur for this year's Asia Dengue Summit #dengue
asiadenguesummit.org

Malaysia’s DCA has given conditional approval for Takeda’s Qdenga dengue vaccine for use in people aged ≥4 years, after evaluation of the vaccine’s safety, efficacy, and quality. WHO has recommended use of Qdenga in places with high dengue disease burden.
codeblue.galencentre.org/2024/02/09/mal…

Just wrapped up 4 intense days at PEDICON in Kochi, Kerala! Soaked in invaluable insights on pediatric infectious diseases, especially dengue. Grateful for the knowledge and connections made!

TAK-003 dengue vaccine as a new tool to mitigate dengue in countries with a high disease burden - The Lancet Global Health thelancet.com/journals/langl…

TAK-003 dengue vaccine as a new tool to mitigate dengue in countries with a high disease burden - The Lancet Global Health thelancet.com/journals/langl…

Long-term efficacy and safety of a tetravalent dengue vaccine (TAK-003): 4·5-year results from a phase 3, randomised, double-blind, placebo-controlled trial - The Lancet Global Health thelancet.com/journals/langl…