Hot off the presses: Nano vs. Molecular: Optical Imaging Approaches to Detect & Monitor Tumor #Hypoxia - a new review by NMIN's Gang Zheng Lab & trainees Princess Margaret Cancer Centre @Yulin_Mo_UofT Advanced Sci News Institute of Medical Science Medical Biophysics University of Toronto bit.ly/39qabsS onlinelibrary.wiley.com/doi/10.1002/ad…

Neuron cell migration. Looking for connection: #neuroscience

It’s only a correlation don’t jump to conclusions

Are you curious about using organic dyes in your microscopy experiments but not sure where to start? This Perspective from Luke Lavis and Jon Grimm introduces readers to the world of dyes and their pros and cons for biological applications. nature.com/articles/s4159…

Very excited to share this PNASNews paper on the mechanism of tissue-specific #mRNA delivery using SORT #LNPs . Here we provide evidence for an endogenous targeting mechanism. Congrats to Sean and Qiang! @UTSWNews @utswBMEprogram pnas.org/content/118/52…

Seven technologies set to shake up science in 2022 go.nature.com/3FZBC9P

Have fun at my first #TorontoMarathon !!

New content online: A pyroptosis nanotuner for cancer therapy dlvr.it/SQvz1x

3D view of clathrin & caveolae at the cell membrane #ET

Gangsters reunion at the NanoMedicines Innovation Network Scientific Meeting! 🎉Congrats Yulin Mo and Michael Valic on your poster awards and Tiffany Ho on your NMIN ATC Silver Certification! 🔥

Fresh new paper from the Zheng lab on ACS Nano ! "Light-Activated siRNA Endosomal Release (LASER) by Porphyrin Lipid Nanoparticles" pubs.acs.org/doi/10.1021/ac… Congrats Yulin Mo and co-authors!

Excited to see this paper is finally out! We have shown that incorporating porphyrin-lipids into the clinically approved Onpattro formulation enables light-activated siRNA endosomal release (LASER). Big thanks to everyone on the paper!

Since the discovery of CRISPR-Cas systems, people have wondered if a similar type of system exists in eukaryotes. Today, we report in nature the characterization of Fanzor, a eukaryotic RNA-guided system that can be reprogrammed for human genome editing. nature.com/articles/s4158…

It’s amazing experience chatting with all the great scientists in the field! I really enjoyed and learned a lot in the LRD conference. Big thanks to Dr. Yvonne Perrie and the organizing committee!

Just out in Nature Reviews Drug Discovery "60-year evolution of #LNP for nucleic acid delivery" by legends Pieter Cullis University of British Columbia and Phil Felgner UC Irvine nature.com/articles/s4157…