I am excited to share my first project in @jwadeharperlab for feedback. We used spatiotemporal proteomics (1) to describe how cells respond to NLRP3 agonists and (2) to profile the proximal proteome as NLRP3 trafficks to the site of inflammasome nucleation harperlab.pubpub.org/pub/nlrp3/

Wang Lab v1.0 assemble!

Published online yesterday in PLOS Biology. Lots of wonderful data telling a great story of another way that Toxoplasma can evade IFNgamma. Thanks to reviewers, editor Tania de Koning-Ward, and journal staff

We have a fully-funded postdoc position in the The Ho Lab in #NYC to study how #membraneproteins drive host-pathogen interactions in #malaria parasites using #CryoEM and #CryoET!🦠❄️🔬Email [email protected] with your CV to apply! tinyurl.com/5n96rkfm #teamtomo

Please RT: our lab @WUSTL Test Account are recruiting two postdoctoral fellows @WUSTLPostdoc to study immune response to #HIV and other #retroviruses. We focus on #HIVcure, viral reservoirs, and #inflammation. For more information, please visit wustl.wd1.myworkdayjobs.com/en-US/External…

We will miss our colleagues at OHSU OHSU School of Medicine, but we are excited to announce that the Zhang Lab of Structural Immunology will move to the Van Andel Institute Van Andel Institute (VAI) in August 2024. We have multiple positions open now. Join our exciting journey 👇

Our pre-print on how the ever mysterious #autophagy pathway in Toxoplasma gondii is required to maintain chronic infection - out now! We provide some insights into the function of TgATG9 and reveal dynamics of autophagosome biogenesis in 3D 🔬 @VernCarruthers

The agenda is set! We have an exciting lineup of speakers for #MNID24. Check the website in the next few days for updates (medschool.umich.edu/events/midwest…). The official deadline passed, but you can still register for a poster, just email the organizers @teresa_omeara Yifan Wang | 王一凡

science.org/content/articl… NIAID News British Society for Parasitology Trends in Parasitology Aust Soc for Para ASP-Parasitologists LabEx ParaFrap Women In Malaria ASTMH NIH ASM Bloodsucking Parasites parasitesrule VEuPathDB Centre For Parasitology Women In Parasitology PEERs in Parasitology (PiP) BiologyofParasitism

My commentary on the closure of VectorBase. Join me in rallying for its sustainable continuation. Comment, repost, and circulate. Let’s ensure this vital resource remains accessible for our global #VectorBiology research community.

Our parasite genome databases are really gone! The lack of communication and scientific vision ⁦NIH⁩ is hard to follow. Colossal mistake! ⁦parasitesrule⁩ ⁦British Society for Parasitology⁩ ⁦National Academy of Sciences⁩ ⁦Science Magazine⁩ ⁦nature⁩ ⁦NIAID News⁩

The Yarovinsky Lab is seeking a molecular parasitologist interested in expanding their knowledge in immunology. This is a fully funded NIH 5-year postdoctoral training opportunity focused on host-parasite interactions and immune response. #Immunoparasitology #mpm2024. Please RT

Critical loss: the effects of VEuPathDB defunding on global health - The Lancet Microbe ⁦parasitesrule⁩ ⁦ASTMH⁩ @nih ⁦NIAID News⁩ ⁦British Society for Parasitology⁩ ⁦Women In Parasitology⁩ ⁦Parasite Slack⁩ #mpm2024 thelancet.com/journals/lanmi…

Excited to share this work from former Pruneda Lab superstar Cam Roberts! Cam tackled the challenge of identifying #ubiquitin regulators secreted by pathogenic bacteria, and found an entirely new type of E3 ligase that regulates P. aeruginosa virulence! biorxiv.org/content/10.110…

Congratulations to Zhijian “James” Chen, 2024 #LaskerAward winner! – “for the discovery of the cGAS enzyme that senses foreign and self DNA, solving the mystery of how DNA stimulates immune and inflammatory responses.” laskerfoundation.org/winners/cgas-e… #Lasker2024 #LaskerLaureate

Introducing the GTs that synthesize the GPI sidechain of T. gondii, PIGE and PIGE. This is the Ph.D. thesis work Julia Alvarez and important collaborative work with UGA CTEGD C. West. With structures in hand, first in vivo description of a parasite with/without its GPI sidechain.

Another pre-print from my PhD work! We explore the role of two orthologs of Atg18/WIPI in Toxoplasma gondii bradyzoite autophagy. 🚨 Spoiler alert: One of them may be more important than the other for autophagy and during chronic infection! @VernCarruthers

RNF213 ubiquitylates LPS but also restricts LPS-free pathogens: bacteria, parasites and viruses! Is RNF213 an amazingly versatile pattern-recognition receptor (#PRR) or does it act downstream of specific PRRs? The answer hot from the EMBO Reports press: embopress.org/doi/full/10.10…

Mitigating racial bias from LLMs is a lot easier than removing it from humans! Can’t believe this happened at the best AI conference NeurIPS Conference We have ethical reviews for authors, but missed it for invited speakers? 😡

Most MIT profs who I know are extremely honest and morally upright. I hope this is an exception.