Mandel-Gutfreund Lab (@yaelmglab) 's Twitter Profile
Mandel-Gutfreund Lab

@yaelmglab

Computational Molecular Biology @Technion @biologytechnion

ID: 1105146466207756289

calendar_today11-03-2019 16:40:24

129 Tweet

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Amir Argoetti (@aargoetti) 's Twitter Profile Photo

Iโ€™m honored and flattered to receive The Prof. David and Harriet Gershon Excellence Fellowship. I would like to thank the Gershon family and committee for choosing me and for appreciating my science and my social activities

Amir Argoetti (@aargoetti) 's Twitter Profile Photo

#lncRNAfeed Does anyone know how many base pairs around the sgRNA are closed by CRISPRi? We are debating knockdown approaches of a nuclear lncRNA that is back to back to a protein-coding gene Mandel-Gutfreund Lab

Amir Argoetti (@aargoetti) 's Twitter Profile Photo

Unfulfilled with its conserved partnership, NORAD found a new match... Please welcome our preprint on how an ALU element equipped NORAD in the arms race against viruses!๐Ÿงต The Unexpected Match: STAT3-NORAD Interaction, a Novel Link in Antiviral Defense biorxiv.org/content/10.110โ€ฆ

Unfulfilled with its conserved partnership, NORAD found a new match...

Please welcome our preprint on how an ALU element equipped NORAD in the arms race against viruses!๐Ÿงต

The Unexpected Match: STAT3-NORAD Interaction, a Novel Link in Antiviral Defense
biorxiv.org/content/10.110โ€ฆ
Amir Argoetti (@aargoetti) 's Twitter Profile Photo

In summary, a surprise twist in evolution unlocked NORAD's new feature! It can now mediate the nuclear entry of STAT3, thereby inhibiting the interferon response in primates. Upon viral infection, NORAD is cleaved, prompting STAT3's exit and activating the antiviral response.

In summary, a surprise twist in evolution unlocked NORAD's new feature!
It can now mediate the nuclear entry of STAT3, thereby inhibiting the interferon response in primates.
Upon viral infection, NORAD is cleaved, prompting STAT3's exit and activating the antiviral response.
Galia Polyak (@galiapolyak) 's Twitter Profile Photo

Check this awesome preprint out ๐Ÿ‘‡๐Ÿ‘‡๐Ÿ‘‡ Amir is one of the most dedicated persons I had the privilege of working with, and I'm super glad his labour of love is finally out๐Ÿ™๐Ÿป

Amir Argoetti (@aargoetti) 's Twitter Profile Photo

Hi RNA feed! Does anyone here know of a small-molecule or non-protein RNAse inhibitor? All the RNase inhibitors I found are large proteins that can disrupt my assay

Amir Argoetti (@aargoetti) 's Twitter Profile Photo

ืื ื™ ื™ื•ื“ืข, ืคื” ื–ื” ืœื ืื™ื ืกื˜ื•ืฉ, ืื‘ืœ ืืคื™ืชื™ ื‘ื’ื˜ื™ื ืœื›ื‘ื•ื“ ื”ื—ื‘ืจื” ื”ืฆืจืคืชื™ื” ืฉืœื™ Galia Polyak ืฉืžืฆื™ื’ื” ื‘ืขื•ื“ ื›ืžื” ืฉืขื•ืช ืืช ื”ืžืืกื˜ืจ ื”ืกื•ืคืจ ืžื•ืฆืœื— ืฉืœื” ื•ืื ื™ ืžืื“ ื’ืื” ื‘ื”! ื•ืื ืืชื ื‘ืžืงืจื” ื‘ื˜ื›ื ื™ื•ืŸ ื”ื™ื•ื ื‘12:30, ืžื•ื–ืžื ื•ืชื™ื ืœืฉืžื•ืข ืขืœ RNA ืจื’ื•ืœื˜ื•ืจื™ ื‘ื”ืชืคืชื—ื•ืช ืขื•ื‘ืจื™ืช (ื•ืœื˜ืขื•ื ืžื”ื‘ื’ื˜ื™ื ๐Ÿ˜‰)

ืื ื™ ื™ื•ื“ืข, ืคื” ื–ื” ืœื ืื™ื ืกื˜ื•ืฉ, ืื‘ืœ ืืคื™ืชื™ ื‘ื’ื˜ื™ื ืœื›ื‘ื•ื“ ื”ื—ื‘ืจื” ื”ืฆืจืคืชื™ื” ืฉืœื™ <a href="/GaliaPolyak/">Galia Polyak</a>  ืฉืžืฆื™ื’ื” ื‘ืขื•ื“ ื›ืžื” ืฉืขื•ืช ืืช ื”ืžืืกื˜ืจ ื”ืกื•ืคืจ ืžื•ืฆืœื— ืฉืœื” ื•ืื ื™ ืžืื“ ื’ืื” ื‘ื”! 

ื•ืื ืืชื ื‘ืžืงืจื” ื‘ื˜ื›ื ื™ื•ืŸ ื”ื™ื•ื ื‘12:30, ืžื•ื–ืžื ื•ืชื™ื ืœืฉืžื•ืข ืขืœ RNA ืจื’ื•ืœื˜ื•ืจื™ ื‘ื”ืชืคืชื—ื•ืช ืขื•ื‘ืจื™ืช (ื•ืœื˜ืขื•ื ืžื”ื‘ื’ื˜ื™ื ๐Ÿ˜‰)
Mandel-Gutfreund Lab (@yaelmglab) 's Twitter Profile Photo

Weโ€™re thrilled to share our new paper! ๐ŸŽ‰ This study reveals how the lncRNA NORAD interacts with STAT3 to regulate the antiviral response. Congratulations to Amir and the entire team for their incredible work! Biology Technion Technion Israel nature.com/articles/s4146โ€ฆ

Technion Israel (@technionlive) 's Twitter Profile Photo

๐ŸŒŸ Viruses vs. Human Cells: The Evolutionary Arms Race๐Ÿงฌ Technion researchers uncover a unique mechanism in human cells that rapidly activates the immune system against viruses. A breakthrough in fighting infections and understanding evolution! ๐Ÿ”ฌ๐Ÿงฌ Study in Nature Communications led

๐ŸŒŸ Viruses vs. Human Cells: The Evolutionary Arms Race๐Ÿงฌ  
Technion researchers uncover a unique mechanism in human cells that rapidly activates the immune system against viruses. A breakthrough in fighting infections and understanding evolution!  ๐Ÿ”ฌ๐Ÿงฌ Study in <a href="/NatureComms/">Nature Communications</a> led