Update: Excited to share that we've expanded our ex vivo #postmortem dataset of #neurodegenerative diseases spanning #Alzheimer's disease & related #dementias to a whopping **135** human brain specimens at 7 #tesla #MRI #neuroscience #neuroimaging Link: arxiv.org/abs/2303.12237

Our latest work combining ex vivo MRI and serial histology of the medial temporal lobe is out now in Nature Communications! Using brains with #Alzheimers disease diagnoses, we characterize the spread and effects of tau across histologically defined MTL subregions. rdcu.be/dJ0LS

Please stop by poster # 169 today Saturday (07/27) Neuroimaging PIA #AAIC2024 #AAIC24 Alzheimer's Association to learn about our new parcellation scheme for 7T ex vivo human brain MRI to perform vertex-wise analysis to link morphometry with histopathology! PICSL Penn Memory Center

🚨Publication alert🚨 New BioFINDER publication co-led by Laura Wisse and Nicola Spotorno: “The MRI signature of alpha-synuclein in asymptomatic stages and a memory clinic population”. Check it out: jamanetwork.com/journals/jaman…

My deep learning algorithm RDA can estimate longitudinal neurodegenerative progression, AND is explainable! Stop by poster #865 to check out how this plot was generated! Neuroimaging PIA #AAIC2024 #AAIC24 Penn Memory Center ISTAART

Please come and learn more about advances in 7T postmortem MRI at my talk tomorrow!! Details here: Date and time: Wed, July 31st at 8 AM in the morning Location: 115 ABC #AAIC2024 #AAIC24 Neuroimaging PIA Alzheimer's Association PICSL Penn Memory Center

Chris Brown from Penn Memory Center and Corey McMillan (he/him/his) shared his hypothesis-driven #PET and #MRI approach this morning at #AAIC2024 — individualized prediction models win supporting network spread hypothesis of #tau.

Very proud to have presented my post in #AAIC24 #AAIC2024 ISTAART for a more sensitive biomarker for neurodegeneration. Really looking forward to this robust method to be evaluated in some clinical trial data in the future!

Wrapping up my #AAIC24 experience in beautiful Philly with a team pic. Proud to be part of this amazing team and grateful for the chance to learn and grow alongside them. We missed having the brilliant Laura Wisse with us this time! Looking forward to next time! Alzheimer's Association

Excited to have the opportunity to present my work at #AAIC2024. Big shoutout to my PhD advisors Dr. David Wolk and Sandhitsu Das , as well as my amazing hippogang labmates for all their support! Alzheimer's Association Penn Memory Center PICSL

Thank you JAGS for publishing my Grandpa’s art and story. 🧠 It’s so meaningful to share his art while living with #Alzheimers. Institute on Aging Penn Memory Center Penn Radiology doi.org/10.1111/jgs.19…

In a first-of-its-kind application, a Penn Medicine research team aims to use T-N mismatch to identify distinct spatial-temporal progression patterns of non-AD pathologies. Xueying Lyu, a PhD student at Penn working on the study presented at #AAIC24. med.upenn.edu/aging/aaic2024…